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Expression data from mouse colorectal cancer grown in non-adipose environment or white adipose environment

ABSTRACT: Expression data from mouse colorectal cancer grown in non-adipose environment or white adipose environment

PROVIDER: PRJNA451409 | ENA |

REPOSITORIES: ENA

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Expression data from mouse colorectal cancer grown in non-adipose environment or white adipose environment

Project description:Cancers located adjacent to adipose tissues often show intrinsic and acquired resistance to antiangiogenic therapy. The resistance is developed potentially via tumor cell metabolic paradigm shift. We use microarrays to detail the gene expression upon tumor grown in the adipose tissues or non-adipose tissues. Inflammatory profiling and fatty acid oxidation related genes have been detected.

2018-04-24 | GSE113507 | GEO

Rat white adipose tissue DIGE-LC-MSMS

Project description:White adipose tissue is a central place to energy storage and a major endocrine organ. However, adipose molecular mechanisms have been poorly studied during prolonged fasting. To fill this gap, the aim of this study was to decipher proteomic regulations in rat adipose tissue during phase 2 (lipid mobilization) and phase 3 (protein catabolism) of prolonged fasting compared to the fed state. Specific responses reflecting adipose tissue inflammation, increased fibrinolysis and a possible protein catabolism-related energy saving mechanism were recorded during phase 3. Differences between internal and subcutaneous adipose tissues were essentially related to lipid metabolism, the response to oxidative stress and energy production. These data thus provide a molecular basis of adipose tissue responses according to the fasting stage.

2021-02-24 | PXD010902 | Pride

Brown versus white tissue adipose selective genes

2007-06-08 | GSE8044 | GEO

Transcription profiling of mouse brown versus white tissue adipose

Project description:The aim of this study was to identify genes expressed selectively in brown adipose tissue as compared to white adipose tissue from the same animals. This analysis provides a gene set that is brown and white adipose selective. Experiment Overall Design: Interscapular brown adipose tissue and epididymal white adipose tissue was carefully dissected from 3 male C57Bl/6 mice. These samples were profiled independently using Affymetrix mouse 430_2 gene arrays, representing 3 biological replicates for each brown and white adipose tissues.

2008-06-15 | E-GEOD-8044 | biostudies-arrayexpress

Mouse interscapular brown, subscapular white and inguinal white adipose tissue

Project description:Adult mouse were kept at room temperature, RNAseq was performed for interscapular brown, subscapular white and inguinal white adipose tissue

2020-07-13 | E-MTAB-9192 | biostudies-arrayexpress

White adipose tissues: amphiregulin overexpression

Project description:Transcriptional profiling of transgenic mice specifically expressing amphiregulin in white adipose tissues. The objective of this study is to explore gene expression profiles of adipose tissues in response to amphiregulin overexpression.

2017-09-15 | GSE103875 | GEO

Effect PPARb/d knockout in white adipose tissue

Project description:Analysis of white adipose tissue of PPARb/d knockout mice. Data may point towards putative target genes of PPARb/d and thus the function of PPARb/d in white adipose tissue. Datasets were used to identify glycogen synthase 2 as novel PPAR target. Keywords: gene expression array-based, count

2007-07-04 | GSE8344 | GEO

Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver

Project description:Cold exposure imposes a metabolic challenge to mammals that must be met by a coordinated repsonse in different tissues to prevent hypothermia. This study reports analysis of transcriptome profiles in brown adipose tissue, liver, white adipose of mice in repsonse to 24 hour cold exposure Total RNA was extracted from brown adipose, whie adipose and liver from cold treated and control plants. 3 replicates of brown adipose and white adipose and 2 replicates of liver samples.

2013-07-08 | E-GEOD-44138 | biostudies-arrayexpress

Loss of miR-22 in white adipose tissue

Project description:We conducted expression profiling of white adipose tissue isolated from WT and miR-22 KO animals. The main work is analysis of the miR-22 function in striated muscle. White adipose tissue (WAT) was analyzed to look at effects in WAT, as that might be induced by metabolic changes in skeletal muscle.

2017-03-13 | E-MTAB-5409 | biostudies-arrayexpress

Comparison of white adipose tissue and bone marrow adipose tissue from New Zealand White rabbits

Project description:Microarray analysis of white adipose tissue (WAT) and bone marrow adipose tissue (BMAT) from 22-week-old or 13-week-old male New Zealand White rabbits. From both cohorts, BMAT was sampled from the distal tibia (dBMAT) and the radius and ulna (ruBMAT), while WAT was sampled from the inguinal (iWAT) and gonadal (gWAT) depots. From the 13-week-old cohort, BMAT was also sampled from the proximal tibia (pBMAT). Sufficient RNA could not be isolated from all tissues for all rabbits, so for some rabbits only a subset of tissues is included.

2019-12-10 | GSE138690 | GEO

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