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H3.3 phosphorylation promotes enhancer acetylation and lineage specification

ABSTRACT: H3.3 phosphorylation promotes enhancer acetylation and lineage specification

PROVIDER: PRJNA471713 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7172880_1.fastq.gz	Fastqsanger.gz
	SRR7172880_2.fastq.gz	Fastqsanger.gz
	SRR7172890_1.fastq.gz	Fastqsanger.gz
	SRR7172890_2.fastq.gz	Fastqsanger.gz
	SRR7172900_1.fastq.gz	Fastqsanger.gz

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H3.3 phosphorylation promotes enhancer acetylation and lineage specification [RNA-seq]

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H3.3 phosphorylation promotes enhancer acetylation and lineage specification [ATAC-seq]

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H3.3 phosphorylation promotes enhancer acetylation and lineage specification [RNA-seq]

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H3.3 phosphorylation promotes enhancer acetylation and lineage specification [ChIP-seq]

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H3.3 phosphorylation promotes enhancer acetylation and lineage specification

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Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation.

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Project description:The re-assembly of chromatin following DNA replication is a critical event in the maintenance of genome integrity. Histone H3 acetylation at K56 and phosphorylation at T45 are two important chromatin modifications that accompany chromatin assembly. Here we report a microarray expression study of the protein kinase Pkc1, histone acetyl transferase Rtt109 and histone H3 in Saccharomyces cerevisiae under conditions of replicative stress.

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