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Genome wide analysis of the upper lumbar spinal cord at 4 days after T9 hemisection injury

ABSTRACT: Genome wide analysis of the upper lumbar spinal cord at 4 days after T9 hemisection injury

PROVIDER: PRJNA474210 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7263730.fastq.gz	Fastqsanger.gz
	SRR7263731.fastq.gz	Fastqsanger.gz
	SRR7263732.fastq.gz	Fastqsanger.gz
	SRR7263733.fastq.gz	Fastqsanger.gz
	SRR7263734.fastq.gz	Fastqsanger.gz

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Genome wide analysis of the upper lumbar spinal cord at 4 days after T9 hemisection injury

Project description:The goal of this study is to elucidate the influence of hemisection injury at thoracic spinal cord (T9) on the upper transcriptome of the upper lumbar spinal cord at acute phase. mRNA profiles of spinal cord at 4 days-post injury and before injury were generated. 72 Differentially Expressed Genes (DEGs) were observed. Our study represents the detailed analysis of transcriptomes of spinal cord distal to the hemisected lesion at acute phase, with biologic replicates, generated by RNA-seq technology.

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Project description:Genome wide analysis of the lower lumbar spinal cord at 4 days after T9 hemisection injury

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Project description:The goal of this study is to elucidate the influence of treadmill training on transcriptome of the upper lumbar spinal cord after thoracic spinal cord hemisection. mRNA profiles of spinal cords at 23 days-post injury with/without treadmill training were generated. The expression levels of 650 genes in the trained animal were increased ( > 2-fold) compared to untrained animals. Our study represents the detailed analysis of transcriptomes of spinal cord distal to the hemisected lesion after treadmill training, with biologic replicates, generated by RNA-seq technology.

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