Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bremerella cremea strain:HEX-1 MGV

ABSTRACT: Bremerella cremea strain:HEX-1 MGV Genome sequencing and assembly

PROVIDER: PRJNA480487 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR8304469_1.fastq.gz	Fastqsanger.gz
	SRR8304469_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

Bremerella cremea strain:HEX-2 MGV

Project description:Bremerella cremea strain:HEX-2 MGV Genome sequencing and assembly

| PRJNA480490 | ENA

Bremerella cremea strain:HEX PRIS-MGV

Project description:Bremerella cremea strain:HEX PRIS-MGV Genome sequencing and assembly

| PRJNA480493 | ENA

Blastopirellula marina strain:HEX PRIS-MGV

Project description:Blastopirellula marina strain:HEX PRIS-MGV Genome sequencing and assembly

| PRJNA435605 | ENA

Blastopirellula marina strain:Hex-1 MGV

Project description:Blastopirellula marina strain:Hex-1 MGV Genome sequencing and assembly

| PRJNA435585 | ENA

Blastopirellula marina strain:Hex-2 MGV

Project description:Blastopirellula marina strain:Hex-2 MGV Genome sequencing and assembly

| PRJNA435601 | ENA

Bremerella cremea

Project description:Blastopirellula cremea overview

| PRJNA480537 | ENA

Hex acts with β-catenin to regulate anterior-posterior

Project description:In Xenopus, establishment of the anterior-posterior axis involves two key signalling pathways, canonical Wnt and Nodal-related TGF-β. There are also a number of transcription factors that feedback upon these pathways. The homeodomain protein Hex, an early marker of anterior positional information, acts as a transcriptional repressor suppressing induction and propagation of the Spemman organiser while specifying anterior identity. We show that Hex promotes anterior identity by amplifying the activity of canonical Wnt signalling. Hex exerts this activity by inhibiting the expression of Tle-4, a member of the Groucho family of transcriptional co-repressors that we identified as a Hex target in embryonic stem (ES) cells and Xenopus embryos. This Hex-mediated enhancement of Wnt signalling results in the up-regulation of the Nieuwkoop centre genes Siamois and Xnr-3 and the subsequent increased expression of the anterior endodermal marker Cerberus and other mesendodermal genes downstream of Wnt signalling. We also identified Nodal as a Hex target in ES cells. We demonstrate that in Xenopus, the Nodal-related genes Xnr-1 and 2, but not 5 and 6, are regulated directly by Hex. The identification of Nodal-related genes as Hex targets explains the ability of Hex to suppress induction and propagation of the organiser. Together these results support a model in which Hex acts early in development to reinforce a Wnt-mediated, Nieuwkoop-like signal to induce anterior endoderm, and later in this tissue to block further propagation of Nodal-related signals. The ability of Hex to regulate the same targets in both Xenopus and mouse implies this model is conserved. Keywords: genetic modification

2006-09-01 | GSE5141 | GEO

Bremerella alba strain:FF15

Project description:Bremerella alba strain:FF15 Genome sequencing and assembly

| PRJNA633004 | ENA

Sphingomonas cremea strain:G124

Project description:Sphingomonas cremea strain:G124 Genome sequencing and assembly

| PRJNA789685 | ENA

Rhodopirellula sp. MGV

Project description:Rhodopirellula sp. MGV Genome sequencing and assembly

| PRJNA394679 | ENA