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Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes [Ribo-Seq]

ABSTRACT: Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes [Ribo-Seq]

PROVIDER: PRJNA480786 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7513745.fastq.gz	Fastqsanger.gz
	SRR7513746.fastq.gz	Fastqsanger.gz
	SRR7513747.fastq.gz	Fastqsanger.gz
	SRR7513748.fastq.gz	Fastqsanger.gz

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Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes

Project description:Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes

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Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes [Mars-seq]

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Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes [Ribo-Seq]

Project description:The Ribo-seq analysis demonstrated that eIF1A is predominantly essential for translation of genes with long 5'UTR genes including cell proliferation and cell cycle progression genes. eIF1A depletion causes broad stimulation of initiation in 5’UTRs at near-cognate AUG codons that diminshes the translation initiation fidelity

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Cancer associated mutants of eIF1A impair Rps3/Rps10 binding and enhance scanning of cell cycle genes

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-07-13 | GSE116983 | GEO