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ABSTRACT: Anti-obesity effects of white ginseng and red ginseng

PROVIDER: PRJNA481605 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7534610_1.fastq.gz	Fastqsanger.gz
	SRR7534610_2.fastq.gz	Fastqsanger.gz
	SRR7534620_1.fastq.gz	Fastqsanger.gz
	SRR7534620_2.fastq.gz	Fastqsanger.gz
	SRR7534611_1.fastq.gz	Fastqsanger.gz

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Project description:Anti-obesity effects of ginseng

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Anti-Stress Effect of Red Ginseng via Repression of PADI4 by ER-beta Stimulation

Project description:Ginseng has been used for anti-stress agents, and its active ingredient, ginsenoside, has similar structure with estrogen. In this study, effects of red ginseng (RG) on gene expressions in immobilization (IMO) stressed mice brain was analyzed by system biology.

2012-03-01 | E-MTAB-856 | biostudies-arrayexpress

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The effects of Korean Red Ginseng on Di-(2-ethylhexyl) phthalate-induced inflammatory response in endometrial cancer cells

Project description:Di-(2-ethylhexyl) phthalate (DEHP) is the most common endocrine disrupting chemical used as a plasticizer. DEHP is associated with the development of endometrium-related diseases through the induction of inflammation. The major therapeutic approaches against endometrial cancer and endometriosis involve the suppression of inflammatory response. Korean red ginseng (KRG) is a natural product with anti-inflammatory and anti-carcinogenic effects. Thus, the purpose of this study is to investigate the effects of KRG on DEHP-induced inflammatory response in endometrial cancer Ishikawa cells.

2022-07-13 | GSE154388 | GEO

Korean Red Ginseng in Treating Patients With Fatigue Caused by Chemotherapy for Colorectal Cancer

Project description:Korean Red Ginseng may improve fatigue in healthy subject. It is not yet known whether Korean Red Ginseng is effective compared with a placebo in chemotherapy. The purpose of this study is to determine whether Korean Red Ginseng is effective in the treatment of the fatigue from colorectal cancer with chemotherapy.(modified FOLFOX-6)

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1, 3-Dicaffeoylquinic acid targeting 14-3-3 τ suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway

Project description:Caffeoylquinic acids are a kind of phenolic acid, a natural component of quinine acids. A number of caffeic acids, which are widely found in plants, are connected by ester bonds. In classic Chinese medicines, including honeysuckle, Eucommia ulmoides and white flower ginseng, caffeoylquinic acids have been identified as a main effective component that exhibits antioxidant, anti-inflammatory, antibacterial and antiviral activities . Studies have shown that some dicaffeoylquinic acids have significant inhibitory effects on melanoma, colorectal cancer, gastric cancer, breast cancer and many other tumours . The development and exploration of the pharmacodynamic effects of dicaffeoylquinic acids will become another hot topic in the development of new drugs.

2021-01-14 | E-MTAB-8051 | biostudies-arrayexpress

Systems biology analysis of Korean red ginseng effects on Immobilization stressed mice brain

Project description:Here we present molecular mechanisms of Korean red ginseng (KRG) on immobilization stresses Keywords: stress response

2009-08-09 | GSE12656 | GEO

Systems biology analysis of Korean red ginseng effects on Immobilization stressed mice brain

Project description:Here we present molecular mechanisms of Korean red ginseng (KRG) on immobilization stresses Keywords: stress response Mice were divided into three groups (3 mice / group): control, stress + no treat, and stress + Korean Red Ginseng (KRG, 100 mg). Stress + KRG group were given KRG 100 mg orally for 7 days and then exposed to immobilization stress for 45 min. stress + no treat group were administrated with phosphate buffer saline (d-PBS, pH 7.4) together with IMO stress for 45 min.

2010-05-15 | E-GEOD-12656 | biostudies-arrayexpress

Label-free quantitative proteomic approach to investigate the effect of heat stress on Panax ginseng leaves

Project description:Ginseng is one of the well-known medicinal plants, exhibiting diverse medicinal effects. Its roots possess anticancer and anti-aging properties and are being used in the medical systems of East Asian countries. Ginseng is grown in low-light and low-temperature conditions and its growth is strongly inhibited at temperatures above 25 ℃. However, the molecular responses of ginseng to heat stress are currently poorly understood, especially at protein level. Therefore, here we utilized a shotgun proteomics approach to investigate the effect of heat stress on ginseng leaves. Total proteins were isolated from control (25 ℃) and ginseng plants exposed to 35 ℃ for 1 and 3 days and subjected to in-solution trypsin digestion. A total of 3,359 ginseng proteins were identified when searched in an in-house developed RNA-seq (PAC-BIO) database.

2018-12-11 | PXD009124 | Pride