Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Farm soil DNRA functional nrfa genes

ABSTRACT: farm soil DNRA functional nrfa genes Raw sequence reads

PROVIDER: PRJNA487712 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7757710.fastq.gz	Fastqsanger.gz
	SRR7757720_1.fastq.gz	Fastqsanger.gz
	SRR7757720_2.fastq.gz	Fastqsanger.gz
	SRR7757711_1.fastq.gz	Fastqsanger.gz
	SRR7757711_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

Project description:DNRA nrfA genes

| PRJNA597679 | ENA

soil functional genes

Project description:soil functional genes Raw sequence reads

| PRJNA804976 | ENA

Farm Animal Exposure, Respiratory Illnesses, and Nasal Cell Gene Expression

Project description:Background: Farm exposures in early life reduce the risks for childhood allergic diseases and asthma. There is less information about how farm exposures relate to respiratory illnesses and mucosal immune development. Objective: We hypothesized that children raised in farm environments have a lower incidence of viral illnesses over the first two years of life than non-farm children. We also analyzed between farm exposures or respiratory illnesses were related to patterns of nasal cell gene expression. Methods: The Wisconsin Infant Study Cohort (WISC) birth cohort enrolled farm and non-farm pregnant women from central Wisconsin. Parents reported prenatal farm and other environmental exposures. Illness frequency and severity were assessed using illness diaries and periodic surveys. Nasopharyngeal cell gene expression at age two years was compared to farm exposure and respiratory illness history. Results: There was a higher rate of respiratory illnesses in the non-farm vs. farm group (rate ratio 0.82 [0.69,0.97], p=0.020), but no significant differences in wheezing illnesses. There was a stepwise reduction in rates of respiratory illnesses in children exposed at least weekly to 0, 1, or ≥2 animals (p=0.006). In analyzing nasal cell gene expression, farm exposures and preceding respiratory illnesses were positively related to gene signatures for mononuclear cells and innate and antimicrobial responses. Conclusions: Children exposed to farms and farm animals had lower rates of respiratory illnesses over the first two years of life. Both farm exposures and preceding respiratory illnesses were associated with increased innate immune responses, suggesting that these exposures stimulate mucosal immune responses to reduce subsequent illness frequency.

2024-01-29 | GSE233761 | GEO

farm-soil

Project description:farm-soil Raw sequence reads

| PRJNA485594 | ENA

qz nrfA cc

Project description:qz nrfA cc Raw sequence reads

| PRJNA903770 | ENA

nrfa global sdiment

Project description:nrfa global sediment Raw sequence reads

| PRJNA626481 | ENA

nrfA gene diversity

Project description:Linking DNRA community structure and activity in a shallow lagoonal estuarine system