Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of spleen tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

ABSTRACT: RNA-seq of spleen tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

PROVIDER: PRJNA495389 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7989632_1.fastq.gz	Fastqsanger.gz
	SRR7989632_2.fastq.gz	Fastqsanger.gz
	SRR7989633_1.fastq.gz	Fastqsanger.gz
	SRR7989633_2.fastq.gz	Fastqsanger.gz
	SRR7989634_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

RNA-seq of spleen tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

Project description:We infected wild type and Elf4 deficient mice with Plasmodium yoelii 17XNL, a non-lethal species, to investigate and compare anti-Plasmodium response of two groups of mice.

2018-10-10 | GSE121037 | GEO

RNA-seq of bone marrow tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

Project description:We infected wild type and Elf4 deficient mice with Plasmodium yoelii 17XNL, a non-lethal species, to investigate and compare anti-Plasmodium response of two groups of mice.

2018-10-10 | GSE121035 | GEO

Plasmodium yoelii yoelii strain:17XNL

Project description:Plasmodium yoelii yoelii strain:17XNL Genome sequencing and assembly

| PRJNA1436 | ENA

RNA-seq of bone marrow tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

Project description:RNA-seq of bone marrow tissue of wild type and Elf4 deficient mice after Plasmodium yoelii 17XNL infection

| PRJNA495386 | ENA

Proteomics approaches for decoding Plasmodium yoelii biology

Project description:Plasmodium yoelii is a rodent parasite commonly used as a model to study liver-stage development in host system during malaria infection. Mass spectrometry-based proteomics approaches helps in understanding the proteomic profiling of parasite and provided opportunities to explore the mechanisms controlling parasite functions. It will further help in identifying new targets for therapeutic interventions, identification of Plasmodium associated virulence in the host. It will also help in the extensive refinement of parasite genome, and understanding of Post-translational modifications (PTM) in Plasmodium yoelii biology. In the present study, we performed a proteomic shotgun analysis of the Plasmodium yoelii 17XNL strain.

2022-04-01 | PXD013932 | Pride

Plasmodium yoelii yoelii 17XNL

Project description:Total comparative RNA sequencing of WT vs. ccr4-1 knockout Plasmodium yoelii

| PRJNA394583 | ENA

Time series of Balb/c spleen infected with Plasmodium yoelii non-lethal vs lethal strains

Project description:Knowledge on the dynamic features of the processes driven by malaria parasites in the spleen, our biggest lymphoid organ, is lacking. We have implemented intravital microscopy and magnetic resonance imaging of the mouse spleen in experimental infections with the Plasmodium yoelii non-lethal (17X) and lethal (17XL) strains. Notably, there was higher parasite accumulation, reduced motility, lost of directionality and different T2 relaxation times only in spleens of mice infected with the 17X strain. Moreover, these differences were associated with the formation of a strain-specific induced spleen tissue barrier, with macrophage-clearance escape, and with cytoadherence of infected reticulocytes to this barrier. This is a novel spleen-immune evasion mechanism in which parasite-induced spleen remodeling and adherence to this organ allow establishment of chronic infections. We performed time-series global transcriptional analyses from spleens of mice infected with the P. yoelii 17X and 17XL strains at days 3, 4, 5, 10% and 50% of parasitemia post-infection, together with non-infected spleens as a reference day 0, using commercially available arrays representing the complete mouse genome (Agilent Whole Mouse Genome G4122A).

2010-10-12 | E-GEOD-17603 | biostudies-arrayexpress

Plasmodium yoelii yoelii

Project description:Plasmodium yoelii yoelii Epigenomics

| PRJNA657308 | ENA

Plasmodium yoelii yoelii strain:17XNL clone 1.1

Project description:Plasmodium yoelii Genome sequencing and assembly, Gene Model Creation

| PRJNA769959 | ENA

Plasmodium yoelii yoelii

Project description:Plasmodium yoelii yoelii Genome sequencing

| PRJNA209080 | ENA