Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identification of Sin3B regulated genes during quiescence

ABSTRACT: Identification of Sin3B regulated genes during quiescence

PROVIDER: PRJNA498664 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8113970.fastq.gz	Fastqsanger.gz
	SRR8113971.fastq.gz	Fastqsanger.gz
	SRR8113972.fastq.gz	Fastqsanger.gz
	SRR8113973.fastq.gz	Fastqsanger.gz
	SRR8113974.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Identification of Sin3B regulated genes during quiescence

Project description:We report differences in gene expression between WT and Sin3B KO T98G cells throughout the cell cycle

2018-10-31 | GSE121857 | GEO

Identification of Sin3B regulated genes in HSCs

Project description:We report differences in gene expression between WT and Sin3B KO HSCs.

2016-10-28 | GSE83218 | GEO

Recruitment of the EMSY/KDM5A/SIN3B complex to target genes is regulated by ZNF131

Project description:Recent work from others and us revealed interactions between the Sin3/HDAC complex, the H3K4me3 demethylase KDM5A, GATAD1 and EMSY. Here, we characterize the EMSY/KDM5A/SIN3B complex in detail by quantitative interaction proteomics and ChIP-sequencing. We identify a novel substoichiometric interactor of the complex, ZNF131, which recruits EMSY to a large number of active, H3K4me3 marked promoters. Interestingly, using an EMSY knock-out line and subsequent rescue experiments, we show that EMSY is in most cases positively correlated with transcriptional activity of its target genes and stimulates cell proliferation. Finally, by immunohistochemical staining of primary breast tissue microarrays we find that EMSY/KDM5A/SIN3B complex subunits are frequently overexpressed in primary breast cancer cases in a correlative manner. Taken together, these data open venues for exploring the possibility that sporadic breast cancer patients with EMSY amplification might benefit from epigenetic combination therapy targeting both the KDM5A demethylase and histone deacetylases.

2017-12-11 | GSE75566 | GEO

E2F1-regulated genes

Project description:Identification of E2F1-regulated genes that modulate the transition from quiescence into DNA synthesis, or have roles in apoptosis, signal transduction, membrane biology, and transcription repression. Keywords: other

2003-07-16 | GSE498 | GEO

Identification of genes regulated by Bcl11b

Project description:Identification of genes regulated by Bcl11b

| PRJNA856979 | ENA

Identification of genes regulated by DUSP4

Project description:Identification of genes regulated by DUSP4

| PRJNA607449 | ENA

Global identification of retinoic acid regulated genes

Project description:Global identification of retinoic acid regulated genes

| PRJNA544092 | ENA

Genome-wide maps of Sin3A and Sin3B binding in C2C12 myoblasts and differentiated myotubes

Project description:Sin3A and Sin3B bind to distinct and overlapping target sites. Sin3 proteins bind to distinct sites in cycling myoblasts whereas there is a converge of Sin3A and Sin3B proteins to sites in differentiated myotubes. We identified a subset of Sin3 target genes involved in muscle differentiation and physiology and showed that conditional ablation of Sin3 proteins in vivo in mouse results in sarcomere defects Examination of Sin3A and Sin3B binding during myogenesis

2011-01-01 | E-GEOD-22554 | biostudies-arrayexpress

Transcription profiling of mouse NIH3T3 fibroblasts to investigate E2F1-regulated genes

2008-06-13 | E-GEOD-498 | biostudies-arrayexpress

Identification of Nrf2 regulated genes by RNA sequencing

Project description:Identification of Nrf2 regulated genes by RNA sequencing

| PRJNA451433 | ENA