Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life in Papua New Guinea

ABSTRACT: Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life in Papua New Guinea

PROVIDER: PRJNA507439 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8257900.fastq.gz	Fastqsanger.gz
	SRR8257910.fastq.gz	Fastqsanger.gz
	SRR8257920.fastq.gz	Fastqsanger.gz
	SRR8257930.fastq.gz	Fastqsanger.gz
	SRR8257940.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 50

Similar Datasets

Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life in Papua New Guinea

Project description:This study examines the global transcriptomic profiles in peripheral blood of Papua New Guinea newborns at birth (D0) comparing with follow up at day 1 (D1), day 3 (D3), or day 7 (D7) post birth.

2019-03-20 | GSE123070 | GEO

Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life

Project description:Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life

| PRJNA436923 | ENA

Small Sample-Big Data: Integrative Indexed Systems Biology Reveals Dramatic Molecular Ontogeny over the First Week of Human Life

Project description:Systems biology provides a powerful approach to unravel complex biological processes yet it has not been applied systematically to samples from newborns, a group highly vulnerable to a wide range of diseases. Published methods rely on blood volumes that are not feasible to obtain from newborns. We optimized methods to extract transcriptomic, proteomic, metabolomic, cytokine/chemokine, and single cell immune phenotyping data from <1ml of blood, a volume readily obtained from newborns. Furthermore, indexing to baseline and applying innovative integrative computational methods that address the challenge of few data points with many features enabled identification of robust findings within a readily achievable sample size. This approach uncovered dramatic changes along a stable developmental trajectory over the first week of life. The ability to extract information from ‘big data’ and draw key insights from such small sample volumes will enable and accelerate characterization of the molecular ontogeny driving this crucial developmental period.

2019-03-20 | GSE111404 | GEO

Papua New Guinea birds

Project description:Papua New Guinea birds Genome sequencing and assembly

| PRJNA637995 | ENA

Leaf samples pilot study Papua New Guinea

Project description:Pilot study on leaves from Papua New Guinea showing soil toxicity, extracted in RNAlater in one case and MQ water in another, also MQ blanks

2023-05-25 | MSV000092034 | MassIVE

Sediment Metagenomes Papua New Guinea

Project description:Marine metagenomes and metatranscriptomes from 3 sediment samples along a pH gradient in Papua New Guinea

| PRJEB9383 | ENA

Pygoscelis papua

Project description:Pygoscelis papua overview

| PRJNA491768 | ENA

Mastigias papua

Project description:Mastigias papua overview

| PRJNA992609 | ENA