Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Conserved Transcriptomic Profiles Underpin Monogamy across Vertebrates

ABSTRACT: Conserved Transcriptomic Profiles Underpin Monogamy across Vertebrates

PROVIDER: PRJNA508211 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8275030.fastq.gz	Fastqsanger.gz
	SRR8275030_1.fastq.gz	Fastqsanger.gz
	SRR8275030_2.fastq.gz	Fastqsanger.gz
	SRR8275031.fastq.gz	Fastqsanger.gz
	SRR8275031_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 29

Similar Datasets

Conserved Transcriptomic Profiles Underpin Monogamy across Vertebrates

Project description:We compare fore- and mid-brain transcriptomes of reproductive males in monogamous and non-monogamous species pairs of Peromyscus mice, Microtus voles, parid songbirds, dendrobatid frogs, and Xenotilapia species of cichlid fishes. Our study provides evidence of a universal transcriptomic mechanism underlying the evolution of monogamy in vertebrates.

2018-12-18 | GSE123301 | GEO

Conserved transcriptomic profiles underpin monogamy across vertebrates.

Project description:Social monogamy, typically characterized by the formation of a pair bond, increased territorial defense, and often biparental care, has independently evolved multiple times in animals. Despite the independent evolutionary origins of monogamous mating systems, several homologous brain regions and neuropeptides and their receptors have been shown to play a conserved role in regulating social affiliation and parental care, but little is known about the neuromolecular mechanisms underlying monogamy on a genomic scale. Here, we compare neural transcriptomes of reproductive males in monogamous and nonmonogamous species pairs of Peromyscus mice, Microtus voles, parid songbirds, dendrobatid frogs, and Xenotilapia species of cichlid fishes. We find that, while evolutionary divergence time between species or clades did not explain gene expression similarity, characteristics of the mating system correlated with neural gene expression patterns, and neural gene expression varied concordantly across vertebrates when species transition to monogamy. Our study provides evidence of a universal transcriptomic mechanism underlying the evolution of monogamy in vertebrates.

| S-EPMC6347671 | biostudies-literature

Distinct molecular profiles underpin mild to moderate equine asthma cytological profiles

Project description:Distinct molecular profiles underpin mild to moderate equine asthma cytological profiles

| PRJNA1161698 | ENA

A conserved notochord enhancer controls pancreas development in vertebrates

Project description:A conserved notochord enhancer controls pancreas development in vertebrates

| PRJEB36984 | ENA

Transcriptomic analyses of renal allograft biopsies reveal conserved rejection signatures and molecular pathways

Project description:Transcriptomic analyses of renal allograft biopsies reveal conserved rejection signatures and molecular pathways. GEO SuperSeries. This dataset is part of the TransQST collection.

2009-02-24 | E-GEOD-9493 | biostudies-arrayexpress

CEBPA binding in five vertebrates

Project description:CEBPA binding in five vertebrates

| PRJEB2006 | ENA

Distinct molecular profiles underpin mild to moderate equine asthma cytological profiles

Project description:This project used a state-of-the-art, multi-omics approach to improve our understanding of the aetiopathogenesis of a highly prevalent, performance-limiting disorder of racehorses; mild to moderate equine asthma (MMEA). This advanced knowledge is a prerequisite to improving prophylactic, management and therapeutic options for this condition. Although a number of risk factors for MMEA have been identified, incomplete understanding of the precise aetiopathogenesis of this syndrome means that options for intervention are currently limited. This study aimed to apply a multi-omic approach, reveal key inflammatory pathways involved in inflammatory cell recruitment to the lower airways and highlight pathways specific to different MMEA inflammatory cell profiles (MMEA endotypes). Thus, we compared BALF cell gene and protein expression data from horses with normal bronchoalveolar lavage fluid (BALF) cytology (n = 8) with those isolated from horses with neutrophilic (n = 4), mastocytic (n = 8), mixed neutrophilic/mastocytic (n=4) and mixed eosinophilic/mastocytic (n=3) inflammation. Analyses on transcriptomic and proteomic data derived from BALF cells from horses with neutrophilic cytology showed enrichment in classical inflammatory pathways, while horses with mastocytic cytology showed enrichment in pathways involved in hypersensitivity reactions related to non-classical inflammation that could mimic a Th2 immune response. The mixed eosinophilic/mastocytic group also presented with a non-classical inflammatory profile while, the mixed neutrophilic/mastocytic group revealed profiles consistent with both neutrophilic inflammation and hypersensitivity. Our adopted multi-omics approach (both gene and protein expression) has enabled a more holistic assessment of the immunological status of the lower airways associated with the different cytological profiles of equine asthma.

2024-12-05 | GSE277308 | GEO

Metabolic adaptations underpin resistance to histone acetyltransferase inhibition

Project description:Metabolic adaptations underpin resistance to histone acetyltransferase inhibition

| PRJNA868737 | ENA

Comparative 3D Genome Architecture in Vertebrates

Project description:Comparative 3D Genome Architecture in Vertebrates

| PRJNA704983 | ENA

Conserved transcriptomic signatures and protein markers in cellular senescence models

Project description:Conserved transcriptomic signatures and protein markers in cellular senescence models

| PRJNA987602 | ENA