Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

PROseq to profile activated transcription in bone marrow-derived macrophages from C57BL/6 mice

ABSTRACT: PROseq to profile activated transcription in bone marrow-derived macrophages from C57BL/6 mice

PROVIDER: PRJNA508523 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8283310_1.fastq.gz	Fastqsanger.gz
	SRR8283310_2.fastq.gz	Fastqsanger.gz
	SRR8283303_1.fastq.gz	Fastqsanger.gz
	SRR8283303_2.fastq.gz	Fastqsanger.gz
	SRR8283304_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

PROseq to profile activated transcription in bone marrow-derived macrophages from C57BL/6 mice

Project description:We characterized active transcription in conditions of resting and LPS stimualtion in BMDMs

2020-04-20 | GSE123370 | GEO

Comparison of C57Bl/KalwRij mouse bone marrow to C57BL6 mouse bone marrow

Project description:Multiple myeloma is a fatal hematological malignancy. In order to develop effective therapeutic approaches, it is critical to understand the pathogenesis of myeloma. The Radl 5T model of multiple myeloma is a clinically relevant murine model where myeloma spontaneously occurs in aged, in-bred C57BlKalwRij mice and can be propagated by intravenous inoculation of 5T myeloma cells into mice of the same strain. Importantly inoculation of 5T myeloma cells into C57Bl6 mice does not result in myeloma, demonstrating that the bone marrow (BM) microenvironment of the C57BlKalwRij strain provides a unique and permissive milieu for myeloma development. We hypothesized that cells of the BM microenvironment may provide essential stimuli for the development of multiple myeloma in vivo. We aim to determine the differences in expression within the bone marrow of C57Bl/KalwRij mice. Comparison of C57Bl/KalwRij mouse bone marrow to C57BL6 mouse bone marrow

2011-08-18 | E-GEOD-31532 | biostudies-arrayexpress

Expression data from primary bone marrow-derived wild-type C57BL/6 and bcl6 knockout macrophages

Project description:We used microarrays to compare gene expression changes in macrophages caused by deletion of bcl6. Keywords: BCL6 deletion compared to wild-type Primary bone marrow-derived macrophages were isolated from C57BL/6 mice transplanted and reconstituted with wild type or bcl6 knockout bone marrow.

2012-06-07 | E-GEOD-16527 | biostudies-arrayexpress

Expression data from bone marrow-derived macrophages

2016-03-11 | GSE63653 | GEO

Expression data from bone marrow-derived macrophages

Project description:To identify factors that could explain why mice transplanted with Vim deficient bone marrow display decreased atherosclerosis despite increased inflammation, we performed global gene expression profiling of bone-marrow derived macrophages from vimentin-deficient or wild-type littermates on C57BL/6 background. We elucidated the role of vimentin in atherogenic low-density receptorâ deficient mice after bone marrow transplantation from vimentin-deficient mice.

2016-03-11 | E-GEOD-63653 | biostudies-arrayexpress

Comparison of C57Bl/KalwRij mouse bone marrow to C57BL6 mouse bone marrow

2011-08-19 | GSE31532 | GEO

CEBPB Immunoprecipitation from Bone Marrow Derived Macrophages

Project description:Data from the immunoprecipitation of CEBPB from bone marrow derived macrophages.

2020-03-17 | MSV000085112 | MassIVE

C/EBPepsilon ChIP-sequencing of C57BL/6 mice bone marrow cells

Project description:To characterize the genome wide C/EBPepsilon binding sites, ChIP-sequencing with C57BL/6 mice bone marrow cells were performed. To prevent artifact from PCR amplifiation, sequencing or antibody specificity, two controls of input DNA and ChIP-sequencing of C/EBPepsilon knock-out bone marrow cells were used. Two data sets derived from two anti-C/EBPepsilon antibodies, N-terminal (GTX109155) and C-terminal (SC-158) antibody against wild type and C/EBPepsilon knock-out bone marrow cells were generated.

2017-06-02 | GSE73844 | GEO

PROseq (Precision Run-On sequencing) to capture nascent RNA of wild type and mutant mouse embryonic stem cells

Project description:Precision Run-On Sequencing (PROseq) data for wild type (WT) and mutant mouse embryonic stem cells from Kreibich et al., 2022. PROseq data was obtained by permeabilizing the cells, performing a 2 biotin run-on reaction using biotin-11-UTP and biotin-11-CTP and subsequent enrichments steps for biotinylated RNA during the library preparation. This results in the enrichment of nascent transcripts, including enhancer RNA. Data in this experiment comprises PROseq data obtained from WT mouse embryonic stem cells (ES) and DNA methylation mutants (DNMT TKO ES and TET TKO ES). Comparing the PROseq data obtained from these different cell lines enables the detection of changes in the activity of cis-regulatory elements upon changes in DNA methylation.

2023-02-06 | E-MTAB-12601 | biostudies-arrayexpress

Transcriptional profile of bone marrow-derived macrophages from Cd28 KO mice

Project description:Analysis of the transcriptome of bone marrow-derived macrophages from Cd28 KO mice. Methods: C57BL/6J (WT) and Cd28 KO (B6.129S2-Cd28tm1Mak/J) mice were used. Bone marrow-derived macrophages were obtained by flushing the femurs of 6- to 10-wk-old C57BL/6, and Cd28 KO mice, and culturing cells during 7 days in DMEM supplemented with 10% FCS and 50 mM 2-ME, containing human M-CSF (25 ng/ml), with cytokine addition every 2 days.

2022-12-01 | GSE157837 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data