Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Diverse mammalian retinal ganglion cell types revealed by single cell transcriptome profiling

ABSTRACT: Diverse mammalian retinal ganglion cell types revealed by single cell transcriptome profiling

PROVIDER: PRJNA509760 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8315020_1.fastq.gz	Fastqsanger.gz
	SRR8315020_2.fastq.gz	Fastqsanger.gz
	SRR8315021_1.fastq.gz	Fastqsanger.gz
	SRR8315021_2.fastq.gz	Fastqsanger.gz
	SRR8315018_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Diverse mammalian retinal ganglion cell types revealed by single cell transcriptome profiling

Project description:By single-cell RNA-sequencing (scRNA-seq) analysis, we classify adult mouse RGCs into 28 types, which can be distinguished by distinct sets of characteristic genes or even by single gene markers.

2021-12-11 | GSE123758 | GEO

Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]

Project description:This study aimed to characterize the transcriptomes of adult retinal ganglion cells (RGCs). The physiological properties of these cells were characterized first in non-dissociated retinal tissue. With that information recorded, the cells were isolated for transcriptome profiling.

2019-11-01 | GSE115379 | GEO

Direct induction of retinal ganglion cell-like neurons

Project description:Mouse embryonic fibroblasts were reprogrammed into retinal ganglion cell-like neurons by overexpressing Ascl1/Brn3b/Isl1 transcription factor combination in 13 days.

2020-09-30 | GSE140128 | GEO

Direct induction of retinal ganglion cell-like neurons

Project description:Retinal ganglion cells (RGCs) are the projection neurons in the retina that connect the visual sensing tissue to the brain. We found that Ascl1/Brn3b/Isl1 transcription factor combination can quickly and efficiently reprogramming mouse embryonic fibroblasts (MEFs) into retinal ganglion cell-like neurons (iRGCs). Using RNA-seq, we analyzed the transcriptomes of MEFs infected with Ascl1/Brn3b/Isl1-overexpressing viruses on day 2 or day 7 of reprogramming, or the final iRGCs on day 13 of reprogramming.

2020-09-30 | GSE140689 | GEO

Genetic signatures of retinal ganglion cells revealed through single cell profiling [dissociated RGC]

Project description:This study aimed to characterize the transcriptomes of adult retinal ganglion cells (RGCs). These cells were isolated through their expression of a TdTomato molecule that would only turn on when Cre was present. Cre was controlled by the Parvalbumin promoter.

2019-11-01 | GSE115332 | GEO

Genetic signatures of retinal ganglion cells revealed through single cell profiling

Project description:Genetic signatures of retinal ganglion cells revealed through single cell profiling

| PRJNA474729 | ENA

Direct induction of retinal ganglion cell-like neurons

Project description:Direct induction of retinal ganglion cell-like neurons

| PRJNA588391 | ENA

Atoh7-independent specification of retinal ganglion cell identity

Project description:Atoh7-independent specification of retinal ganglion cell identity

| PRJNA658977 | ENA

Direct induction of retinal ganglion cell-like neurons

Project description:Direct induction of retinal ganglion cell-like neurons

| PRJNA590512 | ENA

Subcellular expression profiling of the growth cones of retinal ganglion cells (RGC)

Project description:Cue-directed axon guidance depends partly on local translation in growth cones. Many mRNA transcripts are known to reside in developing axons yet little is known about their subcellular distribution or, specifically, which transcripts are in growth cones. Laser capture microdissection (LCM) was used to isolate the growth cones of retinal ganglion cell (RGC) axons of two vertebrate species, mouse and Xenopus, coupled with unbiased genome-wide microarray profiling. Localized mRNA from the isolated growth cones of Xenopus laevis and Mus musculus retinal ganglion cells were subjected to microarray analysis

2010-11-23 | E-GEOD-25166 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data