Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Staphylococcus aureus

ABSTRACT: Atopic Dermatitis

PROVIDER: PRJNA512846 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR11016771_1.fastq.gz	Fastqsanger.gz
	SRR11016771_2.fastq.gz	Fastqsanger.gz
	SRR11016772_1.fastq.gz	Fastqsanger.gz
	SRR11016772_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 241

Similar Datasets

GNPS - Staphylococcus aureus SA113 - Mice atopic dermatitis experiments

Project description:GNPS - Staphylococcus aureus SA113 - Mice atopic dermatitis experiments and culture of SA113

2019-03-16 | MSV000083584 | GNPS

Staphylococcus aureus

Project description:Staphylococcus aureus genome sequencing and assembly: atopic dermatitis

| PRJNA511152 | ENA

Staphylococcus aureus

Project description:Staphylococcus aureus isolated from human skin including atopic dermatitis patients

| PRJDB6497 | ENA

Staphylococcus aureus

Project description:Whole genome sequence of a Staphylococcus aureus associated with severe atopic dermatitis

| PRJNA431177 | ENA

Metagenome sequencing of feces of mouse treated D-galactose or not

Project description:D-galactose orally intake ameliorate DNCB-induced atopic dermatitis by modulating microbiota composition and quorum sensing. The increased abundance of bacteroidetes and decreased abundance of firmicutes was confirmed. By D-galactose treatment, Bacteroides population was increased and prevotella, ruminococcus was decreased which is related to atopic dermatitis.

2022-04-29 | E-MTAB-11632 | biostudies-arrayexpress

Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis

Project description:Clinical overlaps between psoriasis and atopic dermatitis are sometimes undiscernible, and there is no consensus whether to treat the overlap phenotype as psoriasis or atopic dermatitis. We enrolled patients diagnosed with either psoriasis or atopic dermatitis, and clinically re-stratified them into classic psoriasis, classic atopic dermatitis, and the overlap phenotype between psoriasis and atopic dermatitis. We compared gene expression profiles of lesional and nonlesional skin biopsy tissues between the three comparison groups. Global mRNA expression and T-cell subset cytokine expression in the skin of the overlap phenotype were consistent with the profiles of psoriasis and different from the profiles of atopic dermatitis. Unsupervised k-means clustering indicated that the best number of distinct clusters for the total population of the three comparison groups was two, and the two clusters of psoriasis and atopic dermatitis were differentiated by gene expression. Our study suggests that clinical overlap phenotype between psoriasis and atopic dermatitis has dominant molecular features of psoriasis, and genomic biomarkers can differentiate psoriasis and atopic dermatitis at molecular levels in patients with a spectrum of psoriasis and atopic dermatitis.

2023-06-24 | GSE182740 | GEO

Genome-wide binding profile of the AhR transcription factor in keratinocytes

Project description:Atopic dermatitis is increasing worldwide, correlating with air pollutions. Various organic components of pollutants activate transcription factor AhR (aryl-hydrocarbon receptor). We have established AhR-CA mice, whose keratinocytes express constitutive-active AhR, and these mice developed atopic dermatitis-like frequent scratching and allergic inflammation. In this study we performed ChIP-seq analyses and identified keratinocyte-specific AhR target genes, including inflammatory cytokines Tslp and IL33, and neurotrophic factor Artemin. While AhR-CA mice exhibited epidermal hyperinnervation and alloknesis leading to hypersensitivity to pruritus, blockade of Artemin alleviated these phenotypes. AhR-CA mice showed scratching-induced barrier insufficiency and enhanced sensitization to epicutaneously-applied antigens, recapitulating human atopic dermatitis. Consistently, AhR activation and Artemin expression was detected in the epidermis of atopic dermatitis patients and keratinocytes exposed to air pollutants. Thus, AhR in keratinocytes senses the environmental stimuli and responds to them through moderating inflammation. We propose a mechanism in which air pollution induces atopic dermatitis through AhR activation.

2016-11-13 | GSE72455 | GEO

Staphylococcus aureus

Project description:Molecular characterization of Staphylococcus aureus that correlate with the disease activity and clinical features of atopic dermatitis (AD).

| PRJDB13052 | ENA

GNPS - Staphylococcus aureus with Solid Phase Extraction

Project description:MS/MS spectra were collected from Staphylococcus aureus bacteria isolated from patients with Atopic Dermatitis from lesional and nonlesional sites. Extractions were performed using 50/50 vol/vol ethyl acetate/methanol and extracts were loaded on SPE cartridges (Oasis HLB, Hydrophilic-Lipophilic-Balance, 30 mg with particle sizes of 30 um) before LC-MS/MS analysis.

2019-02-08 | MSV000083423 | GNPS

EGR1 increases the innervation density of epidermal sensory neurons via upregulation of ARTN in keratinocytes in atopic dermatitis

Project description:Atopic dermatitis (AD) is the chronic inflammatory skin disease accompanied with severe pruritus. To explore the roles of EGR1 in atopic dermatitis and the relationship between EGR1 and pruritus-scratching behavior, we used a atopic dermatitis-like mouse model driven by house dust mite (HDM) treatment in wild type and EGR1 KO mice, followed with RNA-sequencing analysis.

2024-01-15 | GSE214750 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data