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ABSTRACT: Ornithorhynchus anatinus (platypus) genome assembly, mOrnAna1

PROVIDER: PRJNA513296 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	RZJT02.dat.gz	Other
	RZJT02.fasta.gz	Fasta.gz
	RZJT02.master.dat	Other
	RZJU02.dat.gz	Other

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Project description:Small RNA pathways play evolutionarily conserved roles in gene regulation and in defense from pathogenic and parasitic nucleic acids. The character and expression patterns of small RNAs show conservation throughout animal lineages, but specific animal clades also show variations on these recurring themes, including species-specific small RNAs. The monotremes, with only platypus and four species of echidna as extant members, represent the basal branch of the mammalian lineage. Here, we examine the small RNA pathways of monotremes by deep sequencing of six platypus and echidna tissues. We find that highly conserved microRNA species display their signature tissue-specific expression patterns. In addition, we find a large rapidly-evolving cluster of miRNAs on platypus chromosome X1 which is unique to monotremes. Platypus and echidna testes contain a robust piRNA system which appears to be participating in ongoing transposon defense. Keywords: piRNA

2008-05-21 | GSE10571 | GEO

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