Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ribosome profiling in transgenic and HEK293T cells treated with NAEK

ABSTRACT: Ribosome profiling in transgenic and HEK293T cells treated with NAEK

PROVIDER: PRJNA513305 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8404140.fastq.gz	Fastqsanger.gz
	SRR8404141.fastq.gz	Fastqsanger.gz
	SRR8404134.fastq.gz	Fastqsanger.gz
	SRR8404135.fastq.gz	Fastqsanger.gz
	SRR8404136.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Ribosome profiling in transgenic and HEK293T cells

Project description:Ribosome profiling in transgenic and HEK293T cells

| PRJNA420695 | ENA

Ribosome profiling in transgenic and HEK293T cells treated with NAEK

Project description:To investigate whether natural TAG was decoded by stably transfected Mb pyltRNA in transgenic cells, their cell lysate was subjected to ribosome profiling, examining the physical locations of ribosomes. HEK293T cells were taken as control.

2020-01-07 | GSE124737 | GEO

Ribosome profiling in transgenic and HEK293T cells

Project description:To investigate whether natural TAG can be decoded by stably transfected pyltRNA, whole cell lysate of transgenic cells was collected 48h after the addition of NAEK and subjected to ribosome profiling, examining the physical locations of ribosomes along 15662 TAG terminated transcripts. And HEK293T cells were taken as control.

2019-08-01 | GSE107588 | GEO

Ribosome profiling data of HEK293T cells treated with C13-benzamidyl cycloheximide

Project description:We performed ribosome profiling in HEK293T cells with treatment with either C13-benzamidyl cycloheximide (hereafter "benzamide") or cycloheximide.

2021-09-28 | GSE184519 | GEO

Ribosome profiling data of HEK293T cells treated with C13-benzamidyl cycloheximide

Project description:Ribosome profiling data of HEK293T cells treated with C13-benzamidyl cycloheximide

| PRJNA764910 | ENA

Ribosome profiling of HEK293T cells overexpressing codon optimized coagulation factor IX.

Project description:Ribosome profiling provides the opportunity to evaluate translation kinetics at codon level resolution. Here, we describe ribosome profiling data, generated from two HEK293T cell lines. The ribosome profiling data are composed of Ribo-seq (mRNA sequencing data from ribosome protected fragments) and RNA-seq data (total RNA sequencing). The two HEK293T cell lines each express a version of the F9 gene, both of which are translated into identical proteins in terms of their amino acid sequences. However, these F9 genes vary drastically in their codon usage and predicted mRNA structure. We also provide the pipeline that we used to analyze the data. Further analyzing this dataset holds great potential as it can be used i) to unveil insights into the composition and regulation of the transcriptome, ii) for comparison with other ribosome profiling datasets, iii) to measure the rate of protein synthesis across the proteome and identify differences in elongation rates, iv) to discover previously unidentified translation of peptides, v) to explore the effects of codon usage or codon context in translational kinetics and vi) to investigate cotranslational folding. Importantly, a unique feature of this dataset, compared to other available ribosome profiling data, is the presence of the F9 gene in two very distinct coding sequences.

| S-EPMC7509596 | biostudies-literature

Ribosome profiling of harringtonine-treated SUM1315 cells

Project description:SUM1315 were treated with harringtonine, and an untreated control sample was taken. Ribosome profiling was performed on these samples.

2016-02-17 | GSE59815 | GEO

Ribosome profiling of Tunicamycin-treated and -untreated 17Cl1 cells

Project description:Ribosome profiling of Tunicamycin-treated and -untreated 17Cl1 cells

| PRJEB18913 | ENA

Ribosome profiling of harringtonine-treated SUM1315 cells

Project description:SUM1315 were treated with harringtonine, and an untreated control sample was taken. Ribosome profiling was performed on these samples. 1 treated and 1 untreated sample

2016-02-17 | E-GEOD-59815 | biostudies-arrayexpress

Ribosome profiling and RNA sequencing of MCF10A cells treated with TGFb

Project description:MCF10A were either untreated or treated with TGFb. RNA sequencing and ribosome profiling was performed.

2017-07-27 | GSE59817 | GEO