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Gene expression and chromatin accessibility of iLSCs vs iBlasts cells

ABSTRACT: Gene expression and chromatin accessibility of iLSCs vs iBlasts cells

PROVIDER: PRJNA514716 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8435060_1.fastq.gz	Fastqsanger.gz
	SRR8435060_2.fastq.gz	Fastqsanger.gz
	SRR8435070_1.fastq.gz	Fastqsanger.gz
	SRR8435070_2.fastq.gz	Fastqsanger.gz
	SRR8435061_1.fastq.gz	Fastqsanger.gz

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Project description:Analysis of nucleosome positioning and chromatin state by using CpG methyltransferase M.SssI to methylate nuclei. Unmethylated regions that gain methylation (low to high beta value) are known to be accessible and nucleosome depleted. Method used to study changes after epigenetic drug treatments identified that majority of demethylation events are not accompanied by chromatin accessibility changes. RNA harvested from cells post epigenetic drug treatment, with 5-Aza-CdR or SAHA

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2020-02-25 | PXD017054 | Pride

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