N6-methyladenosine (m6A) profiling in 60 YRI LCLs
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA515941 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR8462070.fastq.gz | Fastqsanger.gz | |||
| SRR8462080.fastq.gz | Fastqsanger.gz | |||
| SRR8462090.fastq.gz | Fastqsanger.gz | |||
| SRR8462100.fastq.gz | Fastqsanger.gz | |||
| SRR8462110.fastq.gz | Fastqsanger.gz |
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Project description:N6-methyladenosine (m6A), the most abundant messenger RNA (mRNA) modification, has emerged as a critical post-transcriptional mechanism that regulates various aspect of mRNA metabolism including pre-mRNA processing, mRNA export, mRNA stability and translation efficiency. However the genetics basis of m6A is largely unexplored. In this work, we mapped m6A-QTLs in 60 LCLs and used the resulting tens of thousands of QTLs to provide insights to m6A biology and its contribution to human complex trait.
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