Project description:Analysis of splicing defects in Schizosaccharomyces pombe upon chemical genetic inhibition of splicing kinases dsk1, lkh1, and prp4, as well as alanine-mutation of phosphorylated residues in the splicing factors bpb1, prp2, rsd1, srp1, srp2, usp101, usp103, sum3, prp22, cdc5, and cwf22. This study shows the splicing kinase dsk1 modulates splicing efficiency of introns with non-consensus splice sites, likely through phosphorylation of bpb1. Modulation of splicing efficiency of transcripts through kinase signaling pathways may afford the necessary flexibility to tune the gene expression profile in response to environmental and developmental cues.

2015-07-13 | GSE62752 | GEO

Schizosaccharomyces pombe

Project description:Schizosaccharomyces pombe Epigenomics

| PRJNA266732 | ENA

Schizosaccharomyces pombe

Project description:Schizosaccharomyces pombe Epigenomics

| PRJNA239195 | ENA

DNA microarray analyses on Schizosaccharomyces pombe Wild type, Δpka1, Δcgs1, and Δppt1 strains.

Project description:We explored the possibility that the cAMP/PKA pathway affects the expression of the genes involved in Coenzyme Q10 synthesis and other related metabolic pathways. To that end, we performed microarray analyses on Δpka1, Δcgs1, and Δppt1 strains. An article under submission

2019-01-22 | GSE125392 | GEO

Transcriptional response of Schizosaccharomyces pombe to 5-Fluorouracil (5FU)

Project description:We use high-density tiling DNA microarray technology to obtain the specific transcriptome-wide response induced by 5-Fluorouracil (5FU) in the eukaryotic model Schizosaccharomyces pombe.

2013-11-14 | GSE46919 | GEO

Schizosaccharomyces pombe

Project description:Schizosaccharomyces pombe Genome sequencing

| PRJNA248418 | ENA

Schizosaccharomyces pombe

Project description:Schizosaccharomyces pombe Genome sequencing

| PRJNA252642 | ENA