Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome of XP-B/CS cells

ABSTRACT: Transcriptome of XP-B/CS cells

PROVIDER: PRJNA518097 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8512594.fastq.gz	Fastqsanger.gz
	SRR8512595.fastq.gz	Fastqsanger.gz
	SRR8512596.fastq.gz	Fastqsanger.gz
	SRR8512597.fastq.gz	Fastqsanger.gz
	SRR8512598.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Transcriptome of XP-B/CS cells

Project description:We compared the transcriptome of an XP-B/CS cell to that of the recovered cell line

2019-02-01 | GSE125963 | GEO

Expression data from XP-A and XP-V cells after UVC exposure

Project description:XPA is required for Nucleotide Excision Repair system, which could function to repair DNA damage induced by the UV. UV damage on the genomic DNA cannot be removed, thus persistence of damage could affect the transcriptional machinary. We used the microarray to investigate the global expression profiles in the XP-A and XP-V cells in the low dose of UVC comparing with fibroblast from healthy person. Human primary fibroblasts were developed from the skin of healthy person and two XP patients (XP-A and XP-V). We evaluated global expression profiles comparing the UVC-exposed (0.5J/m2, 5J/m2) with non-exposed sample.

2015-07-14 | E-GEOD-70818 | biostudies-arrayexpress

Rhodococcus erythropolis XP strain:XP

Project description:Rhodococcus erythropolis XP strain:XP Genome sequencing

| PRJNA1198704 | ENA

Expression data from XP-A and XP-V cells after UVC exposure

2015-07-14 | GSE70818 | GEO

Project description:XP Raw sequence reads

| PRJNA1116325 | ENA

Rhodococcus erythropolis XP strain:XP

Project description:Rhodococcus erythropolis XP Genome Sequencing

| PRJNA72225 | ENA

Expression data from Healty Control and XP-A melanocytes

Project description:Xeroderma Pigmentosum (XP) is a DNA repair disorder characterized by photosensitivity, resulting in occurrence of freckle-like pigmented maculae and depigmented maculae on sun-exposed areas. XP complementation group A (XP-A) is the most frequent type in Japan, and patients with XP-A present most severe cutaneous and neurological symptoms due to nucleotide excision repair deficiency. Here, we established induced pluripotent stem cells (iPSCs) derived from XP-A patients and successfully differentiated into melanocytes. To elucidate the pathophysiology of XP, we comprehensively analyzed the difference in gene expression between XP-A-iMCs and healthy-control-iPSC-derived melanocytes (HC-iMCs) 4 hours and 12 hours after irradiation with 30 J/m2 or 150 J/m2 of UV-B using microarray analysis.

2022-01-01 | GSE185308 | GEO

Transcriptional responses to UV irradiation in CS-B cells

Project description:Cockayne syndrome B (CSB) protein is a member of the SWI/SNF family and has DNA-dependent ATPase and ATP-dependent chromatin remodeling activities. The CSB protein is missing or altered in CS-B cells. CS-B cells are hypersensitive to UV light and defective in transcription-coupled DNA repair (TCR). TCR efficiently removes a variety of lesions from the transcribed strand of active genes. It has been shown that lesions specifically in the transcribed strand of active genes trigger the induction of apoptosis following UV irradiation. Several DNA damage signaling cascades, including the ATR/Chk1, p38 kinase, p53, and jun N-terminal kinase pathways are activated following UV irradiation. However, the role of TCR in cellular global transcriptional responses to UV irradiation remains to be elucidated. Using oligonucleotide microarray technology, we analyzed the time course of responses of CS-B cells (CS-B) and CS-B cells complemented with wild-type CSB cDNA (CS-B wt). Keywords: UV response, time course, disease state analysis

2007-09-10 | GSE8939 | GEO

Bordetella pertussis CS strain:CS

Project description:Bordetella pertussis CS strain:CS Genome sequencing

| PRJNA777368 | ENA

Phomopsis sp. XP-8 cultivar:Phomopsis sp. XP-8

Project description:XP-8 Raw sequence reads

| PRJNA376863 | ENA