Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [Myc_CaP]

ABSTRACT: Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [Myc_CaP]

PROVIDER: PRJNA521465 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8550070.fastq.gz	Fastqsanger.gz
	SRR8550080.fastq.gz	Fastqsanger.gz
	SRR8550071.fastq.gz	Fastqsanger.gz
	SRR8550081.fastq.gz	Fastqsanger.gz
	SRR8550062.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 20

Similar Datasets

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes

Project description:Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes

| PRJNA521479 | ENA

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [AT_MC]

Project description:Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [AT_MC]

| PRJNA521486 | ENA

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [TRAMP]

Project description:Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [TRAMP]

| PRJNA521468 | ENA

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [CCO19-MC]

Project description:Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [CCO19-MC]

| PRJNA521467 | ENA

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [Myc_CaP]

Project description:Here we show that low dose Oxali, and to a lesser extent other platinoids, can uniquely activate the transcriptional program that controls MHCI antigen processing and presentation. Activation of this program correlates with induction of histone acetylation and enhanced chromatin accessibility. Oxaliplatin also induces NF-kB dependent IFNg receptor 2 (IFNgR2) thereby augmenting the tumor response to exogenous IFNg produced by reinvigorated effector CD8+ T cells.

2021-02-01 | GSE126269 | GEO

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [AT_MC]

2021-02-01 | GSE126287 | GEO

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [TRAMP]

2021-02-01 | GSE126273 | GEO

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [CCO19-MC]

2021-02-01 | GSE126274 | GEO

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-02-01 | GSE126288 | GEO

p300/CBP mediated activation of MHCI machinery and IFNg receptor loci controls chemoimmunotherapy

Project description:p300/CBP mediated activation of MHCI machinery and IFNg receptor loci controls chemoimmunotherapy