Project description:RNA-Seq analysis was performed to define the associated changes in gene expression of skeletal muscle treated with follistatin

2016-09-03 | GSE78965 | GEO

Changes in skeletal muscle gene expression following castration

Project description:Changes in skeletal muscle gene expression following castration

| PRJNA523860 | ENA

The Heritage family study - skeletal muscle gene expression

Project description:The Heritage family study - skeletal muscle gene expression

| PRJNA481004 | ENA

Differential gene expression analysis of follistain treated skeletal muscle

Project description:RNA-Seq analysis was performed to define the associated changes in gene expression of skeletal muscle treated with follistatin Skeletal muscle mRNA profiles from follistatin and control treated tibialis anterior muscles. Acute (3 day treatment, 3 control and 4 follistatin replicates) and chronic (7or 14 day treatment, 3 control and 4 follistatin replicates) timepoints were analysed.

2016-09-03 | E-GEOD-78965 | biostudies-arrayexpress

Gene expression analysis of Ncor1 muscle-specific knockout and PGC-1alpha muscle-specific transgenic skeletal muscle

Project description:In the present study we have studied the mechanistic and functional aspects of NCoR1 function in mouse skeletal muscle. NCoR1 muscle-specific knockout mice exhibited an increased oxidative metabolism. Global gene expression analysis revealed a high overlap between the effects of NCoR1 deletion and peroxisome proliferator-activated receptor (PPAR) gamma coactivator 1alpha (PGC-1alpha) overexpression on oxidative metabolism in skeletal muscle. The repressive effect of NCoR1 on oxidative phosphorylation gene expression specifically antagonizes PGC-1alpha-mediated coactivation of ERRalpha. We therefore delineated the molecular mechanism by which a transcriptional network controlled by corepressor and coactivator proteins determines the metabolic properties of skeletal muscle, thus representing a potential therapeutic target for metabolic diseases.

2013-01-08 | GSE40439 | GEO

Porphyromonas gingivalis affect gene expression in skeletal muscle, tibialis anterior muscle.

Project description:Porphyromonas gingivalis affect gene expression in skeletal muscle, tibialis anterior muscle.

| PRJNA609279 | ENA