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The regeneration transcriptome of corticospinal neurons

ABSTRACT: The regeneration transcriptome of corticospinal neurons

PROVIDER: PRJNA523844 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8611730_1.fastq.gz	Fastqsanger.gz
	SRR8611730_2.fastq.gz	Fastqsanger.gz
	SRR8611740_1.fastq.gz	Fastqsanger.gz
	SRR8611740_2.fastq.gz	Fastqsanger.gz
	SRR8611731_1.fastq.gz	Fastqsanger.gz

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The regeneration transcriptome of corticospinal neurons

Project description:In the present study, we identify transcriptional mechanisms associated with corticospinal regeneration. We took advantage of the ability of NPC grafts to support corticospinal regeneration, together with a genetic mouse model (Glt25d2-GFP-L10a mice, in which a bacterial artificial chromosome (BAC) codes for GFP-tagged polyribosomes in layer 5b cortical neurons) to selectively enrich actively translated mRNA pools from layer Vb cortical projection neurons containing corticospinal neurons (Doyle et al., Cell 2008).

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