Project description:The conservation and development of chicken has considerably affected human activities, but the admixture history of chicken breeds has so far been poorly demonstrated especially for Chinese indigenous breeds. Using genotypes from 580961 single nucleotide polymorphism markers scored in 1201 animals, we evaluate the genetic diversity (heterozygosity and proportion of polymorphic markers), Linkage disequilibrium (LD) decay, population structure (principal component analysis and neighbor-joining tree), genetic differentiation (FST and genetic distance) and migration events (Treemix and f-statistics) of eight domesticated chicken breeds. All population analytical methods reveal patterns of hybridization which occurred after divergence in Tibetan chicken. We argue that chicken migration and admixture followed by trade have been important forces in shaping modern Chinese chicken genomic variation. Moreover, isolation by distance may play critical role in the shaping genomic variation within Eurasia continent chicken breeds.

2019-10-07 | GSE127968 | GEO

Affymetrix SNP array data for acute lymphoblastic leukemia samples

Project description:Affymetrix SNP array data for acute lymphoblastic leukemia samples

| PRJNA812429 | ENA

Affymetrix SNP array data for chicken responses to glycoconjugate vaccination against Campylobacter jejuni

Project description:Affymetrix SNP array data for chicken responses to glycoconjugate vaccination against Campylobacter jejuni

| PRJNA752761 | ENA

Affymetrix SNP array data for an INAD patient

Project description:Affymetrix SNP array data for an INAD patient

| PRJNA977698 | ENA

Affymetrix SNP array data for HNSCC samples

Project description:Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from cryopreserved HNSCC samples.

2016-03-29 | GSE74555 | GEO

Affymetrix SNP array data for T-cell acute lymphoblastic leukemia samples

Project description:Affymetrix SNP array data for T-cell acute lymphoblastic leukemia samples

| PRJNA1113980 | ENA