Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Indoor metagenome

ABSTRACT: Bacterial and fungal diversity of ancient Rotunda of Sts. Felix and Adauctus of Wawel Royal Castle in Krakow, Poland

PROVIDER: PRJNA526129 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10230700_1.fastq.gz	Fastqsanger.gz
	SRR10230700_2.fastq.gz	Fastqsanger.gz
	SRR10230701_1.fastq.gz	Fastqsanger.gz
	SRR10230701_2.fastq.gz	Fastqsanger.gz
	SRR10230702_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 32

Similar Datasets

indoor metagenome

Project description:Bacterial and fungal diversity of indoor exhibitory rooms of Wawel Royal Castle in Krakow, Poland

| PRJNA646878 | ENA

indoor metagenome

Project description:indoor fungal diversity

| PRJNA290304 | ENA

Gene expression during desiccation and rehydration of the desert alga Flechtneria rotunda

Project description:F. rotunda suffers dramatic gene expression changes during water loss.

2020-06-25 | GSE133352 | GEO

indoor metagenome

Project description:Bacterial, Archaeal and Fungal biodiversity in biodeterioration of historic buildings

| PRJNA274593 | ENA

indoor metagenome

Project description:International Space Station Microbial Observatory - Microbial Diversity

| PRJNA319355 | ENA

indoor metagenome

Project description:Microbial diversity on kitchen sinks and bathroom tiles

| PRJNA384634 | ENA

indoor metagenome

Project description:Indoor Rock Climbing holds SSU rRNA gene diversity

| PRJNA207668 | ENA

Elemental sulfur enhances the anti-fungal effect of Lacticaseibacillus rhamnosus Lcr35

Project description:Lacticaseibacillus rhamnosus Lcr35 is a well-known bacterial strain whose efficiency in preventing recurrent vulvovaginal candidiasis has been largely demonstrated in clinical trials. The presence of sodium thiosulfate (STS) has been shown to enhance its ability to inhibit the growth of C. albicans strains. In this study, we confirmed that Lcr35 has a fungicidal effect not only on the planktonic form of C. albicans but also on other life forms such as hypha and biofilm. Transcriptomic analysis showed that the presence of C. albicans induced a metabolic adaptation of Lcr35 potentially associated with a competitive advantage over yeast cells. However, STS alone had no impact on the global gene expression of Lcr35, which is not in favor of the involvement of an enzymatic transformation of STS. Comparative gas chromatography- mass spectrometry analysis of the organic phase from cell-free supernatant (CFS) fractions obtained from Lcr35 cultures performed in the presence and absence of STS identified elemental sulfur (S0) in the samples initially containing STS. In addition, the anti-candida activity of CFS from STS-containing cultures was shown to be pH-dependent and occurred at acidic pH lower than 5. We next investigated the antifungal activity of lactic acid and acetic acid, the two main organic acids produced by Lactobacillus spp. The two molecules affected the viability of C. albicans but only at pH 3.5 and in a dose-dependent manner, an antifungal effect that was enhanced in samples containing STS in which the thiosulfate was decomposed into S0. In conclusion, the use of STS as an excipient in the manufacturing process of Lcr35 exerted a dual action since the production of organic acids by Lcr35 facilitates the decomposition of thiosulfate into S0, thereby enhancing the bacteria’s own anti-fungal effect.

2024-01-08 | GSE242938 | GEO

Project description:Selenomonas felix genome

| PRJEB21319 | ENA

Whole brain gene expression in Lake Malawi cichlid F1 hybrids

Project description:Most behaviors are associated with heritable genetic variation. Genetic mapping has revealed genomic regions or, in a few cases, specific genes explaining part of this variation. However, understanding how genetic divergence shapes behavioral evolution remains unclear. Here we analyze the evolution of an innate extended phenotype: bower building among male cichlid fish of Lake Malawi, which build bowers of two types, pits and castles. F1 hybrids of pit-digging and castle-building species perform sequential construction of first pit and then castle bowers. Analysis of brain gene expression in these hybrids showed that genes near behavior-associated variants display behavior-dependent allele-specific expression with preferential expression of the pit-species allele during pit digging, and of the castle-species allele during castle building. These genes are highly enriched for functions and pathways involved in neurodevelopment and neural plasticity. Our results suggest that natural behaviors can be associated with complex genetic architectures that alter behavior via cis-regulatory differences whose effects on gene expression are specific to the behavior itself.

2017-06-01 | GSE97490 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data