Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Rhinolophus ferrumequinum (greater horseshoe bat) genome assembly, mRhiFer1

PROVIDER: PRJNA526698 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR11780525_1.fastq.gz	Fastqsanger.gz
	SRR11780525_2.fastq.gz	Fastqsanger.gz
	SRR11780526_1.fastq.gz	Fastqsanger.gz
	SRR11780526_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 15

Similar Datasets

Rhinolophus ferrumequinum isolate:MPI-CBG mRhiFer1

Project description:Rhinolophus ferrumequinum (Greater horseshoe bat) genome sequencing and assembly, primary haplotype, v1

| PRJNA489106 | ENA

Rhinolophus ferrumequinum isolate:MPI-CBG mRhiFer1

Project description:Rhinolophus ferrumequinum (Greater horseshoe bat) genome sequencing and assembly, alternate haplotype, v1

| PRJNA489105 | ENA

Project description:Intestine transcriptome in hibernating mammals (the greater horseshoe bat, Rhinolophus ferrumequinum)

| PRJNA434558 | ENA

Rhinolophus ferrumequinum

Project description:greater horseshoe bat

| PRJNA13678 | ENA

Maintenance of Neural Activities in Torpid Rhinolophus ferrumequinum Bats Revealed by 2D Gel-based Proteome Analysis

Project description:Bats are the only mammals capable of self-powered flying. Many bat species hibernate in winter. A reversible control of cerebral activities is critical for bats to accommodate a repeated torpor-arousal cycle during hibernation. Little is known about the molecular mechanism that regulates neuronal activities in torpid bats. In this study, brain proteins were fractionated and compared between torpid and active Rhinolophus ferrumequinum bats.

2017-05-11 | PXD005158 | Pride

mRhiHip

Project description:Rhinolophus hipposideros (lesser horseshoe bat)

| PRJEB75441 | ENA

Abortive infection of bat fibroblasts with SARS-CoV-2

Project description:Bats are tolerant to highly pathogenic viruses such as Marburg, Ebola, and Nipah, suggesting the presence of a unique immune tolerance toward viral infection. Here, we compared SARS-CoV-2 infection of human and bat (Rhinolophus ferrumequinum) pluripotent cells and fibroblasts. Since bat cells do not express an ACE2 receptor that allows virus infection, we transduced the human ACE2 receptor into the cells and found that transduced cells can be infected with SARS-CoV-2. Compared to human ESCs-hA, infected bat iPSCs-hA produced about a 100-fold lower level of infectious virus and displayed lower toxicity. In contrast, bat fibroblasts (BEF-hA) produced no infectious virus while being infectable and synthesizing viral RNA and proteins, suggesting abortive infection. Indeed, electron microscopy failed to detect virus-like particles in infected bat fibroblasts in contrast to bat iPSCs or human cells, consistent with the latter producing infectious viruses. This suggests that bat somatic but not pluripotent cells have an effective mechanism to control virus replication. Consistent with previous results by others, we find that bat cells have a constitutively activated innate immune system, which might limit SARS-CoV-2 infection compared to human cells.

2024-10-15 | GSE274964 | GEO

mRhiHip2 hap2

Project description:Rhinolophus hipposideros (lesser horseshoe bat) genome assembly, mRhiHip2 haplotype 2

| PRJEB76909 | ENA

mRhiHip2 hap1

Project description:Rhinolophus hipposideros (lesser horseshoe bat) genome assembly, mRhiHip2 haplotype 1

| PRJEB76910 | ENA

Rhinolophus ferrumequinum

Project description:Targeted genome sequencing of the greater horseshoe bat.

| PRJNA13677 | ENA