Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

ABSTRACT: Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

PROVIDER: PRJNA527289 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8734760.fastq.gz	Fastqsanger.gz
	SRR8734770.fastq.gz	Fastqsanger.gz
	SRR8734761.fastq.gz	Fastqsanger.gz
	SRR8734771.fastq.gz	Fastqsanger.gz
	SRR8734762.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

Project description:Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. The dataset contains transcriptomes from two brain regions, temporal and cingulate cortex, for each individual, providing a valuable resource to explore the biology of the human brain in Rett syndrome.

2019-05-01 | GSE128380 | GEO

Transcriptome Analysis Of Human Rett Syndrome Brain

Project description:Transcriptome analysis of postmortem brain samples frrom frontal and temporal cortex of Rett Syndrome cases and matched controls. These data identify genes differentially expressed in postmortem brain tissue from Rett Syndrome cases. Total RNA was extracted from 100mg of postmortem brain tissue.

2015-11-24 | E-GEOD-75303 | biostudies-arrayexpress

Transcriptome Analysis Of Human Rett Syndrome Brain

2015-11-24 | GSE75303 | GEO

Whole Genome Bisulfite Sequencing of Rett Syndrome and Control Human BA9 Cortex

Project description:Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in the gene encoding methyl CpG binding protein 2 (MeCP2) that occur sporadically in 1:10,000 female births. RTT is characterized by a period of largely normal development followed by regression in language and motor skills at 6-18 months of age. To investigate alterations in DNA methylation in RTT, we performed whole genome bisulfite sequencing on brodmann area 9 of human cortex from RTT and matched controls.

2019-09-17 | GSE119980 | GEO

Transcriptional landscape of different brain regions in a Rett syndrome mouse model

Project description:We propose to investigate differential gene expression in Hippocampus and Frontal cortex of MeCP2 knock-out to gain more resolution on transcriptomic changes that occur in the Rett syndrome mouse model

2018-09-30 | GSE60219 | GEO

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain.

Project description:Rett syndrome is an X-linked neurodevelopmental disorder caused by mutation in the methyl-CpG-binding protein 2 gene (MECP2) in the majority of cases. We describe an RNA sequencing dataset of postmortem brain tissue samples from four females clinically diagnosed with Rett syndrome and four age-matched female donors. The dataset contains 16 transcriptomes, including two brain regions, temporal and cingulate cortex, for each individual. We compared our dataset with published transcriptomic analyses of postmortem brain tissue from Rett syndrome and found consistent gene expression alterations among regions of the cerebral cortex. Our data provide a valuable resource to explore the biology of the human brain in Rett syndrome.

| S-EPMC7305197 | biostudies-literature

Whole Genome Bisulfite Sequencing of Rett Syndrome and Control Human BA9 Cortex

Project description:Whole Genome Bisulfite Sequencing of Rett Syndrome and Control Human BA9 Cortex

| PRJNA490890 | ENA

Epigenome analysis of Rett syndrome monozygotic twins samples

Project description:Genome wide DNA methylation profiling of Rett syndrome monozygotic twins. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles in primary skin fibroblast cells from Rett syndrome monozygotic twins. Bisulphite converted DNA from the 2 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip

2012-12-27 | E-GEOD-43141 | biostudies-arrayexpress

Epigenome analysis of Rett syndrome monozygotic twins samples

2012-12-27 | GSE43141 | GEO

ATAC-seq from posterior cingulate cortex (ENCSR729FNL)

Project description:human UMB4727 posterior cingulate cortex For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2021-03-29 | GSE169891 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data