Comparing 3D genome organization in multiple species using Phylo-HMRF
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA528916 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR8782020_1.fastq.gz | Fastqsanger.gz | |||
| SRR8782020_2.fastq.gz | Fastqsanger.gz | |||
| SRR8782021_1.fastq.gz | Fastqsanger.gz | |||
| SRR8782021_2.fastq.gz | Fastqsanger.gz | |||
| SRR8782022_1.fastq.gz | Fastqsanger.gz |
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Project description:We developed a continuous-trait probabilistic model to identify genome-wide evolutionary patterns of 3D genome structures based on multi-species Hi-C data. We applied the proposed method to analyzing cross-species Hi-C data from the same cell type in multiple primate species. The results showed that the proposed method enables discovery of distinct Hi-C contact frequency evolutionary patterns across species.
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