Project description:To investigate the protective effect of Fascin1 inhibitor NP-G2-044 against chondrocyte dedifferentiation, we stimulated murine chondrogenic cell line ATDC5 cells with IL-1β to induce dedifferentiation, and with or without NP-G2-044 treatment. Gene expression profiling analysis was performed using data obtained from RNA-seq of three independent experiments.
Project description:To determine the signaling pathway involved in LS-1-2-mediated tumor inhibition, we performed genome-wide gene expression by comparing HCT116 cells with and without LS-1-2treatment.