Project description:Knocking down YTHDF3 in breast cancer cells resulted in an altered gene expression profile N6-methyl-adenosine (m6A) is the most prevalent internal chemical modification in eukaryotic messenger RNAs and emerging as a critical mRNA chemical mark that mediates post-transcriptional gene expression regulation. YTHDF3 facilitates translation and decay of m6A-modified mRNAs. However, the role for YTHDF3 protein in breast cancer brain metastasis remain to be elucidated. We found that YTHDF3 is overexpressed in brain metastasis of breast cancer cells. Our study will characterize the expression profiling in YTHDF3 silencing breast cancer cells compared to shControl breast cancers cells. The objectives are to identify expression profiles that are specific to shYTHDF3 breast cancer cell to identify new the signaling pathway of YTHDF3 for brain metastasis of breast cancer cells.

2020-09-30 | GSE129946 | GEO

miRNA expression in breast cancer cell lines

Project description:miRNA expression in breast cancer cell lines

| PRJNA497259 | ENA

Gene expression of mouse oral cancer cell lines

Project description:Gene expression of mouse oral cancer cell lines

| PRJNA579101 | ENA