Project description:We sought to determine how a cystic fibrosis isolate of Stenotrophomonas maltophilia responds to relevant pH gradients (pH 5, 7, and 9) by growing the bacterium in phosphate buffered media and conducting RNAseq experiments. Our data suggests acidic conditions are stressful for strain FLR19, as it responded by increasing expression of stress-response and antibiotic-resistance genes.
Project description:Stenotrophomonas sp. SY1 showed the highly efficient detoxification to cadmium and chromium. Thus, the purpose of this project is to clarify the mechanism of detoxification to cadmium and chromium in strain SY1.