Project description:In this study, we present the complete mitogenome and a phylogenetic analysis of Muraenesox cinereus determined by long PCR and primer walking methods. The complete mitochondrial genome is a circular molecule of 17,987 bp in length and contains the same set of 37 mitochondrial genes [13 protein-coding genes, 2 ribosomal RNA (rRNA), and 22 transfer RNA (tRNA)], and a control region as other bony fishes. The base composition of the entire mitogenome showed a slight excess of AT bias. The entire mitogenome data produced in this study provides the genomic resources available for future evolutionary studies.
Project description:There is still a big debate about the correlation between melanosis coli (MC) and carcinoma. We used HTA2.0 to investigate the expression changes of lncRNAs and mRNAs in human colonic mucosa with or without MC and try to investigate MC from gene aspect, eventually to demonstrate whether there’s a certain correlation between MC and carcinoma. GeneChip® Human Transcriptome Array 2.0 (HTA 2.0) microarrays were adopted. The expression profile of lncRNAs and mRNA were tested in five colon tissue biopsy specimen of MC patients and five demographically-matched controls.