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Distal regulation mediated Core Transcriptional Regulatory Circuitry in Esophageal Squamous Cell Carcinoma [ChIP-Seq Drug]

ABSTRACT: Distal regulation mediated Core Transcriptional Regulatory Circuitry in Esophageal Squamous Cell Carcinoma [ChIP-Seq Drug]

PROVIDER: PRJNA544319 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR9110272.fastq.gz	Fastqsanger.gz
	SRR9110273.fastq.gz	Fastqsanger.gz
	SRR9110274.fastq.gz	Fastqsanger.gz
	SRR9110275.fastq.gz	Fastqsanger.gz
	SRR9110276.fastq.gz	Fastqsanger.gz

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Distal regulation mediated Core Transcriptional Regulatory Circuitry in Esophageal Squamous Cell Carcinoma [ChIP-Seq Drug]

Project description:In esophageal squamous cell carcinoma (ESCC), the core regulatory circuitry is ill-defined and the limited clinical approaches are available currently for the treatment of ESCC. Here, using enhancer profiling and CRC programme, we generated ESCC-dependent epigenomic-transcriptional regulatory circuitry, elaborated the exquisite work model mediated by core TFs and SEs through physical interaction between enhancers and promoter, and identified the crucial target of ESCC regulatory network.

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