Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: sacha inchi oil afect Rattus norvegicus albus colonic contents Raw sequence reads

PROVIDER: PRJNA544985 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR9186260.fastq.gz	Fastqsanger.gz
	SRR9186270.fastq.gz	Fastqsanger.gz
	SRR9186280.fastq.gz	Fastqsanger.gz
	SRR9186290.fastq.gz	Fastqsanger.gz
	SRR9186300.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 56

Similar Datasets

Project description:Sacha inchi peptide hydrolysates affect Rattus norvegicus colonic contents Raw sequence reads

| PRJNA660528 | ENA

Rattus norvegicus

Project description:sacha inchi oil affect Rattus norvegicus liver Transcriptome

| PRJNA544970 | ENA

Project description:Sacha inchi oil affect Rattus norvegicus brain transcriptome

| PRJNA555136 | ENA

rat gut metagenome

Project description:Rattus norvegicus albus colonic contents Raw sequence reads

| PRJNA541098 | ENA

Project description:Sacha inchi peptide hydrolysates affect Rattus norvegicus renal Transcriptome

| PRJNA674726 | ENA

Project description:Polysaccharides from Sacha Inchi shell affect Mus musculus albus caecum contents Raw sequence reads

| PRJNA1099161 | ENA

Sacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats

Project description:Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia, hepatic steatosis and inflammatory infiltration in high-fat diet (HFD)-fed rats. Sacha inchi oil administration reversed gut microbiota dysbiosis and altered the gut microbiota metabolome and in particular prevented bile acid dysmetabolism caused by a HFD. Sacha inchi oil intake ameliorated hepatic lipid dysmetabolism in HFD-fed rats, via potentiating the biosynthesis and reuptake of bile acids, reducing the de novo lipogenesis, promoting fatty acid beta-oxidation, and alleviating the dysregulation of glycerolipid, glycerophospholipid, and sphingolipid metabolisms. The results showed that dietary sacha inchi oil can alleviate gut microbiota dysbiosis and reduce lipid dysmetabolism in HFD rats, and provide novel insights into the molecular mechanisms by which plant-derived ω-3 PUFAs prevent the development of hyperlipidaemia.

2022-02-21 | MTBLS1225 | MetaboLights

Project description:Jie-Yu decoction affect Rattus norvegicus colonic contents Raw sequence reads

| PRJNA724928 | ENA

Project description:Semen Sojae Praeparatum affect Rattus norvegicus colonic contents Raw sequence reads

| PRJNA648293 | ENA

Rattus norvegicus albus

Project description:Rattus norvegicus albus Raw sequence reads

| PRJNA683142 | ENA