Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

ABSTRACT: A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

PROVIDER: PRJNA549394 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7822424_1.fastq.gz	Fastqsanger.gz
	SRR7822424_2.fastq.gz	Fastqsanger.gz
	SRR7822425_1.fastq.gz	Fastqsanger.gz
	SRR7822425_2.fastq.gz	Fastqsanger.gz
	SRR7822426_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 14

Similar Datasets

A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

Project description:A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

| PRJNA533256 | ENA

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [ChIP-Seq]

Project description:A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [ChIP-Seq]

| PRJNA549398 | ENA

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq]

| PRJNA490516 | ENA

A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

Project description:To elucidate whether lncRNA-AK096729 plays a role in colorectal cancer tumorigenesis, a RNA-seq analysis was performed to compare the gene expression profiles of lncRNA-AF339830 siRNA and control siRNA transfectants.

2019-10-01 | GSE129950 | GEO

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq]

Project description:To elucidate whether lncRNA-AF339830 plays a role in colorectal cancer tumorigenesis, a RNA-seq analysis was performed to compare the gene expression profiles of lncRNA-AF339830 siRNA and control siRNA transfectants.

2019-07-08 | GSE119866 | GEO

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [ChIP-Seq]

Project description:To elucidate whether lncRNA-AF339830 plays a role in colorectal cancer tumorigenesis, a Chip-seq analysis was performed to compare the change of c-myc genome-wide binding of lncRNA-AF339830 siRNA and control siRNA transfectants.

2019-07-08 | GSE132887 | GEO

A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-07-08 | GSE132888 | GEO

LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc.

Project description:Long non-coding RNAs (lncRNAs) contribute to colorectal cancer (CRC). However, the role of lncRNAs in CRC metabolism, especially glucose metabolism remains largely unknown. In this study, we identify a lncRNA, GLCC1, which is significantly upregulated under glucose starvation in CRC cells, supporting cell survival and proliferation by enhancing glycolysis. Mechanistically, GLCC1 stabilizes c-Myc transcriptional factor from ubiquitination by direct interaction with HSP90 chaperon and further specifies the transcriptional modification pattern on c-Myc target genes, such as LDHA, consequently reprogram glycolytic metabolism for CRC proliferation. Clinically, GLCC1 is associated with tumorigenesis, tumor size and predicts poor prognosis. Thus, GLCC1 is mechanistically, functionally, and clinically oncogenic in colorectal cancer. Targeting GLCC1 and its pathway may be meaningful for treating patients with colorectal cancer.

| S-EPMC6677832 | biostudies-literature

IMP1-interactive lncRNA regulates human endoderm differentiation via stabilizing WNT targets

Project description:IMP1-interactive lncRNA regulates human endoderm differentiation via stabilizing WNT targets

| PRJNA779086 | ENA

A novel meiosis-related lncRNA, Rbakdn, contributes to spermatogenesis by stabilizing Ptbp2

Project description:A novel meiosis-related lncRNA, Rbakdn, contributes to spermatogenesis by stabilizing Ptbp2

| PRJNA761683 | ENA