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The effect of attenuated Salmonella typhimurium on the tumor epithelium in mouse colorectal cancer model

ABSTRACT: The effect of attenuated Salmonella typhimurium on the tumor epithelium in mouse colorectal cancer model

PROVIDER: PRJNA560971 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10004500.fastq.gz	Fastqsanger.gz
	SRR10004501.fastq.gz	Fastqsanger.gz
	SRR10004502.fastq.gz	Fastqsanger.gz
	SRR10004503.fastq.gz	Fastqsanger.gz
	SRR10004504.fastq.gz	Fastqsanger.gz

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The effect of attenuated Salmonella typhimurium on the tumor epithelium in mouse colorectal cancer model

Project description:Bacterial cancer therapy (BCT) shows great promise for treatment of solid tumors, yet basic mechanisms of bacterial-induced tumor suppression remain undefined. We aimed to better understand the tumor epithelium-targeted mechanisms of BCT by using mouse models of intestinal tumorigenesis to assess the effectiveness and mechanisms of treatment with aromatase A-deficient Salmonella typhimurium (STm) delivered by oral gavage.

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