Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq from the liver and ileum of mice on ND, WD, and WD with either Lactobacillus gasseri or Lactobacillus johnsonii

ABSTRACT: RNA-seq from the liver and ileum of mice on ND, WD, and WD with either Lactobacillus gasseri or Lactobacillus johnsonii

PROVIDER: PRJNA560977 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10004600.fastq.gz	Fastqsanger.gz
	SRR10004700.fastq.gz	Fastqsanger.gz
	SRR10004601.fastq.gz	Fastqsanger.gz
	SRR10004701.fastq.gz	Fastqsanger.gz
	SRR10004602.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 196

Similar Datasets

Lactobacillus johnsonii NCC comparative genomics with L. iatae

Project description:Whole genome DNA microarray designed for the probiotic L. johnsonii strain NCC533 was used for comparative genomic hybridization (CGH) of L. johnsonii ATCC 33200T, L. johnsonii BL261, L. gasseri ATCC 33323T and L. iatae BL263 (CECT 7394T). In these experiments, the fluorescence ratio distributions obtained with L. iatae and L. gasseri showed characteristic inter-species profiles. The percentage of conserved L. johnsonii NCC533 genes was about 83% in the L. johnsonii strains comparisons and decreased to 51% and 47% for L. iatae and L. gasseri, respectively. These results confirmed the separate status of L. iatae from L. johnsonii at the level of species, and also that it is closer to L. johnsonii than L. gasseri.

2010-11-24 | GSE21627 | GEO

RNA-seq from the liver, ileum, muscle, fat of SPF or GF mice on ND, WD

Project description:RNA seq from the liver, ileum, muscle, fat of SPF or GF mice on ND, WD. "Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12+ macrophages"

2022-05-13 | GSE145052 | GEO

Lactobacillus johnsonii NCC comparative genomics with L. iatae

2010-11-24 | E-GEOD-21627 | biostudies-arrayexpress

RNA-seq from the liver and ileum of mice on ND, WD, and WD with either Lactobacillus gasseri or Lactobacillus johnsonii

Project description:Type 2 diabetes (T2D), the most common form of diabetes, is one of the leading causes of death in the USA. Diet, genetics, environment, and the gut microbes are important factors causing T2D. However, the exactmechanisms by which these factors induce the disease are still unclear. Western diet-induced obesity mimicked the conditions of metabolic syndrome and T2D in mice. Concurrent changes in the bacterial abundance and composition in ileum and stool of mice indicated that the metabolic alterations are associated with microbes.Using a transkingdom network and causal inference analysis, we identified candidate microbes that can potentially mediate changes in metabolic health. In line with our predictions, supplementing mice with the beneficial microbial candidates ameliorated diet induced diabetes in mice. Transcriptomic studies showed that these microbes improved metabolic parameters by regulating mitochondrial processes in the liver. Using systems biology network analyses, followed by experimental validation, we identified key microbes and pathways regulating glucose metabolism. This research aims to uncover the mechanisms of microbiota dependent glucose metabolism to advance treatment of T2D.

2020-09-13 | GSE136033 | GEO

Lactobacillus gasseri

Project description:Lactobacillus gasseri Genome sequencing

| PRJNA371730 | ENA

Lactobacillus gasseri

Project description:Lactobacillus gasseri Genome sequencing

| PRJNA343007 | ENA

Lactobacillus gasseri

Project description:Lactobacillus gasseri Raw sequence reads

| PRJNA760986 | ENA

Lactobacillus gasseri

Project description:Lactobacillus gasseri Raw sequence reads

| PRJNA735330 | ENA

Lactobacillus gasseri

Project description:Lactobacillus gasseri Genome sequencing and assembly

| PRJNA382771 | ENA

Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet induced diabetes

Project description:For WD + Microbes 1 and WD + Microbes 3 experiments, C57BL/6 mice were fed western diet or western diet supplemented with Lactobacillus gasseri or Lactobacillus johnsonii for 8 weeks and serum was collected from each mice. For Pooled_1 (control group, western diet only), and Pooled_2 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For Pooled_3 (western diet + Lactobacillus johnsonii) group, serum from 4 mice was pooled. For Pooled_7 (control group, western diet only), Pooled_8 (western diet + Lactobacillus gasseri) and Pooled_9 (western diet + Lactobacillus johnsonii) groups, serum from 6 mice each was pooled. For WD + Microbes 6 experiment, C57BL/6 mice were fed western diet for 8 weeks. Then, one group (n = 5) of mice was supplemented with Lactobacillus gasseri for 12 weeks along with continuation of western diet and serum was collected. For Pooled_10 (control group, western diet only) and Pooled_11 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For GF + WD + LG experiment, C57BL/6 germ free mice were fed western diet or western diet supplemented with Lactobacillus gasseri for 2 weeks. For Pooled_12 (control, western diet only) and Pooled_13 (western diet + Lactobacillus gasseri) groups, serum from 2 mice each was pooled.

2020-07-28 | ST001436 | MetabolomicsWorkbench

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data