RNA-Sequencing data of coxsackievirus type B3(CVB3) infected human neural progenitor stem cell(hNPC)
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA563356 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR10056421.fastq.gz | Fastqsanger.gz | |||
| SRR10056422.fastq.gz | Fastqsanger.gz | |||
| SRR10056423.fastq.gz | Fastqsanger.gz | |||
| SRR10056424.fastq.gz | Fastqsanger.gz | |||
| SRR10056425.fastq.gz | Fastqsanger.gz |
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Project description:We infected two strains of mice, 129S1/SvImJ and 129X1/SvJ, with coxsackievirus type b3 (CVB3) at a dose of 500 pfu/g. 129S1 mice developed increased cardiopathology despite equal viral replication. We hypothesized that the increased cardiopathology might result from an ongoing pathologic host response that we could characterize by global expression profiling. Gene expression was assessed in hearts from 129S1 and 129X1 mice that were uninfected or infected for 6 days.
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