Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Tracking Epigenetic Modification-Mediated Genome Organization

ABSTRACT: Tracking Epigenetic Modification-Mediated Genome Organization

PROVIDER: PRJNA565701 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10123750_1.fastq.gz	Fastqsanger.gz
	SRR10123750_2.fastq.gz	Fastqsanger.gz
	SRR10123751_1.fastq.gz	Fastqsanger.gz
	SRR10123751_2.fastq.gz	Fastqsanger.gz
	SRR10123752_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

Tracking Epigenetic Modification-Mediated Genome Organization

Project description:Spatiotemporal control of chromatin structure and dynamics at sub-kilobase to megabase scales is essential for genome function. Epigenetic modification plays important roles in transcriptional regulation. How histone marks regulate genome organization at different scales remain unclear. Here we introduce an EpiGo (Epigenetic perturbation induced Genome organization) system to modify hundreds of genomic loci with H3K9me3 spanning megabases on human chromosome 19 and simultaneously track their changes of genome organization. EpiGo-mediated H3K9me3 spreads more extensively in transcriptionally inactive regions than active regions. H3K9 trimethylation of active regions trigger local chromatin compaction without substantial gene silencing. H3K9 trimethylated loci or regions associate with HP1a condensates and adjacent loci with H3K9me3 coalesce over time. H3K9 trimethylation of inactive regions reshape local genome compartmentalization. These results reveal that H3K9me3 mediates local chromatin compaction or genome compartmentalization upon distinct transcriptional states.

2020-11-04 | GSE137469 | GEO

Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice

Project description:Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice

| PRJNA879786 | ENA

Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [Hi-C]

Project description:Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [Hi-C]

| PRJNA879086 | ENA

Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [RNA-Seq]

Project description:Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [RNA-Seq]

| PRJNA879083 | ENA

Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [ChIP-Seq]

Project description:Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [ChIP-Seq]

| PRJNA879791 | ENA

Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [ATAC-Seq]

Project description:Systematic analysis of circadian gene expression mediated by epigenetic modification and 3D genome organization in Rice [ATAC-Seq]

| PRJNA879081 | ENA

Tracking epigenetic changes during human leukemogenesis

Project description:Tracking epigenetic changes during human leukemogenesis

| PRJNA597528 | ENA

FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification

Project description:FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification

| PRJNA1080202 | ENA

FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification [MeRIP-seq]

Project description:FTO suppresses cardiac fibrosis after myocardial infarction via m6A-mediated epigenetic modification [MeRIP-seq]

| PRJNA1080645 | ENA

PRC2 mediated paternal epigenetic inheritance

Project description:PRC2 mediated paternal epigenetic inheritance - E15.5