Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Streptococcus mitis group bacteria

ABSTRACT: Streptococcus mitis, Streptococcus pneumoniae, Streptococcus pseudopneumoniae, Streptococcus oralis. Genome sequencing

PROVIDER: PRJNA573516 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10160911_1.fastq.gz	Fastqsanger.gz
	SRR10160912_1.fastq.gz	Fastqsanger.gz
	SRR10160913_1.fastq.gz	Fastqsanger.gz
	SRR10160914_1.fastq.gz	Fastqsanger.gz
	SRR10160915_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 35

Similar Datasets

Expression analysis of strains Streptococcus pneumoniae KCTC 5080T, Streptococcus mitis KCTC 3556T, Streptococcus oralis KCTC 13048T, and Streptococcus pseudopneumoniae CCUG 49455T

Project description:Investigation of whole genome gene expression level changes in S. pneumoniae KCTC 5080T, S. mitis KCTC 3556T, S. oralis KCTC 13048T, and S. pseudopneumoniae CCUG 49455T. This proves that transcriptional profiling can facilitate in elucidating the genetic distance between closely related strains. A one chip study using total RNA recovered from S. pseudopneumoniae CCUG 49455T with three strain. For the the transcriptome of S. pseudopneumoniae CCUG 49455T was analyzed using the S. pneumoniae R6 microarray platform and compared with those of S. pneumoniae KCTC 5080T, S. mitis KCTC 3556T, and S. oralis KCTC 13048T strains.

2012-04-26 | E-GEOD-37539 | biostudies-arrayexpress

Expression analysis of strains Streptococcus pneumoniae KCTC 5080T, Streptococcus mitis KCTC 3556T, Streptococcus oralis KCTC 13048T, and Streptococcus pseudopneumoniae CCUG 49455T

2012-04-27 | GSE37539 | GEO

Comparative genomic hybridization of Streptococcus mitis B6 and other Streptococcus mitis strains.

Project description:Genomic comparison of Streptococcus mitis B6 and other Streptococcus mitis strains.

2010-01-21 | E-MEXP-2497 | biostudies-arrayexpress

Pathochip of Streptococcus spp surface proteins

Project description:In order to appreciate the presence of surface protein gene homologues in commensal species S. mitis and S. oralis, comparative genomic hybridization studies using DNA microarrays were performed with 8 S. mitis and 11 S. oralis from different geographic locations. The oligonucleotide microarray was designed based on the genomes of S. pneumoniae R6 and TIGR4 as well as S. mitis B6 to include genes of 63 cell surface proteins. The denatured genomic DNA of the S. mitis and S. oralis strains was labeled with Cy3-dCTP and control S. mitis B6 DNA was labeled with Cy5-dCTP. Hybridization was performed following the manufacturers recommendations using an hybridization temperature of 40C for 16 h. For data processing, microarrays were scanned on the laser scanner Pro Scan Array GX (PerkinElmer) with the low resolution of 50 M-5m using ScanArrayExpress Software version 4.0. Photomultiplier tube was adjusted to balance the two fluorescence channels and biochips were scanned with a resolution of 10 M-5m. After elimination of background values fluorescence intensity was determined. Signals that showed an intensity ratio of 0.3 and above were considered to be positive.

2011-09-15 | E-MEXP-3360 | biostudies-arrayexpress

Streptococcus

Project description:Streptococcus mitis/oralis

| PRJDB12916 | ENA

Expression analysis of strains Streptococcus pneumoniae KCTC 5080T, Streptococcus mitis KCTC 3556T, Streptococcus oralis KCTC 13048T, and Streptococcus pseudopneumoniae CCUG 49455T

Project description:Expression analysis of strains Streptococcus pneumoniae KCTC 5080T, Streptococcus mitis KCTC 3556T, Streptococcus oralis KCTC 13048T, and Streptococcus pseudopneumoniae CCUG 49455T

| PRJNA162399 | ENA

Klebsiella pneumoniae peptide hijacks a Streptococcus pneumoniae permease to subvert pneumococcal growth and colonization

Project description:Treatment of pneumococcal infections is limited by antibiotic resistance and exacerbation of disease by bacterial lysis releasing pneumolysin toxin and other inflammatory factors. We identified a novel peptide in the Klebsiella pneumoniae secretome, which enters Streptococcus pneumoniae via its AmiA-AliA/AliB permease. Subsequent downregulation of genes for amino acid biosynthesis and peptide uptake was associated with reduction of pneumococcal growth in defined medium and human cerebrospinal fluid, irregular cell shape, decreased chain length and decreased genetic transformation. The bacteriostatic effect was specific to S. pneumoniae and Streptococcus pseudopneumoniae with no effect on Streptococcus mitis, Haemophilus influenzae, Staphylococcus aureus or K. pneumoniae. Peptide sequence and length were crucial to growth suppression. The peptide reduced pneumococcal adherence to primary human airway epithelial cell cultures and colonization of rat nasopharynx, without toxicity. We also analysed the effect of peptide on the proteome of S. pneumoniae. We found alteration of the proteome by the peptide with some proteins turned on or off in line with the transcriptomic changes. We therefore identified a peptide with potential as a therapeutic for pneumococcal diseases suppressing growth of multiple clinical isolates, including antibiotic resistant strains, while avoiding bacterial lysis and dysbiosis.

2024-04-08 | PXD050408 | Pride

Streptococcus mitis

Project description:Streptococcus mitis genome sequencing

| PRJNA208927 | ENA

A strain of Streptococcus mitis inhibits biofilm formation of caries pathogens via abundant hydrogen peroxide production

Project description:Our group recently transcriptomically characterized coculture growth between Streptococcus mutans and several species of commensal streptococci (Rose et al, 2023; Choi et al 2024). One interaction that stood out was with Streptococcus mitis ATCC 49456, which completely inhibited the growth of S. mutans during biofilm formation. This is due to abudant hydrogen peroxide production by S. mitis ATCC 49456, 3-5x higher than other oral commensal streptococci we have worked with. To understand how the transcriptome of S. mutans is modified in coculture with a high hydrogen peroxide producer, we evaluated the transcriptome during monoculture or coculture growth between the two strains. Our results show differential gene expression (DEGs) in S. mutans that follows other trends we have documented previously with other commensal Streptococcus species, as well as DEGs specific to the interaction with S. mitis.

2024-08-02 | GSE273140 | GEO

Streptococcus mitis

Project description:Streptococcus mitis M3 assembly

| PRJNA308844 | ENA