Project description:Total 48 samples with different ANA titer were analyzed for their gene expression profiles with Illumina HumanWG-6 V3 chips 10 healthy control (HC) samples with high ANA, 7 first degree relative of SLE patientw (FDR) with high ANA, 10 HCs with low ANA, 6 FDR with low ANA, 15 SLE patients (SLE) with high ANA were used for the microarray analysis.