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ABSTRACT: Transcriptome of adult Schistosoma japonicum derived from Oncomelania hupensis bred in permissive and non-permissive areas

PROVIDER: PRJNA579703 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10350471_1.fastq.gz	Fastqsanger.gz
	SRR10350471_2.fastq.gz	Fastqsanger.gz
	SRR10350472_1.fastq.gz	Fastqsanger.gz
	SRR10350472_2.fastq.gz	Fastqsanger.gz
	SRR10350473_1.fastq.gz	Fastqsanger.gz

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Project description:Temporal transcriptome response of Oncomelania hupensis by Schistosoma japonicum invasion

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Project description:Chromosome-level genome assembly of Oncomelania hupensis: the intermediate snail host of Schistosoma japonicum

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Comparative genomic hybridization of Schistosoma japonicum Chinese and Philippine isolates

Project description:Chinese and Philippine strains of the blood fluke Schistosoma japonicum present clear and distinctive phenotypes in areas of fecundity, pathology, drug sensitivity and immunology. Despite these differences large scale sequencing efforts have focused solely on Chinese mainland strain of the parasite. We have undertaken a comparative genomic hybridisation (CGH) approach to highlight some of the structural differences in the genome of two of the major geographical isolates of S. japonicum. We identified seven distinct regions of the S. japonicum genome that present differential CGH between Chinese and Philippine strains of the blood fluke Schistosoma japonicum, representing either deletion or duplication regions in the Philippine strain. Within these regions, genes that may be related to phenotypical differences are identified and discussed. Genomic DNA was isolated from adult (7 week post cercarial challenge) Schistosoma japonicum Chinese and Philippine isolates and separate maleand femalesamples comparatively hybridised on an Agilent customn designed oligo microarray.

2012-07-13 | E-GEOD-39329 | biostudies-arrayexpress

Oncomelania hupensis

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Towards an understanding of the mechanism of hypoevolution of Schistosoma japonicum schistosomula from Microtus fortis

Project description:More than 40 species of mammal have been reported to be infected naturally with Schistosoma japonicum (Chinese mainland strain) in China. The reed vole, Microtus fortis, is the only known mammalian host in which the schistosomes are unable to mature and cause significant pathogenic changes. Gene expression profiling of the 10 day old schistosomula was performed. Microarray analysis was also used to identify differences in gene expression between Schistosoma japonicum schistosomula from BALB/c mice and from Microtus fortis. 10 day old schistosomula were isolated, total RNA obtained and Agilent one colour labeling used. A custom designed Agilent microarray was used to determine what differential gene expression occurs between parasites maintained in either a permissive (mouse) or non-permissive (vole) hosts.

2010-12-02 | E-GEOD-25728 | biostudies-arrayexpress

Oncomelania hupensis hupensis

Project description:Oncomelania hupensis hupensis Raw sequence reads

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Project description:Transcriptomes of Oncomelania hupensis

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Project description:Oncomelania hupensis hupensis isolate:GD Genome sequencing

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comparative proteomics in schistosoma japonicum

Project description:In this study, isobaric tags for relative and absolute quantification (iTRAQ) were used to identify differential expression proteins (DEPs) of adult schistosomes across two different intermediate host development: Oncomelania hupensis (O.hupensis) and Oncomelania weishan (O.weishan).

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Comparative analysis of microRNA expression profiles of adult Schistosoma japonicum isolated from water buffalo and yellow cattle

Project description:To investigate microRNAs (miRNAs) involving in the regulation of the schistosome development and survival, we compared miRNA expression profiles of adult Schistosoma japonicum derived from yellow cattle and water buffalo using high-throughput sequencing with Illumina Hiseq Xten.

2019-05-14 | GSE124351 | GEO

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