Bacteria
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA588972 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Asterionellopsis glacialis A3 microbial consortium MAGs
| PRJNA588964 | ENA
Project description:Asterionellopsis glacialis strain:A3 Genome sequencing and assembly
| PRJNA588343 | ENA
Project description:Asterionellopsis glacialis overview
| PRJNA668210 | ENA
Project description:The study was conducted on a model of Lactiplantibacillus plantarum, one of the most studied species widely used in the food industry as a probiotic microorganism and/or microbial starter culture. As a result of step-by-step selection from the L. plantarum 8p-a3 strain isolated from the «Lactobacterin» probiotic, the L. plantarum 8p-a3-Clr-Amx strain was obtained, showing increased resistance, compared with the parent strain, to amoxicillin-clavulanic acid (MIC 20 mcg/ml) and clarithromycin (MIC 10 mcg/ml). The L. plantarum strain DMC-S1 was isolated from the intestine of Drosophila melanogaster Canton-S line. Extracellular vesicles of this bacterium can play a significant role in the drug-resistance development and host-microbe interactions.
2023-11-01 | PXD046569 | JPOST Repository
Project description:Poplar is a short-rotation woody crop routinely studied because of its importance as a sustainable bioenergy crop. The establishment of a successful poplar plantation partially depends on its rhizosphere, a dynamic zone governed by complex interactions between plant roots and a plethora of commensal, mutualistic, symbiotic, or pathogenic microbes that shape plant fitness. Here, we examined a consortium of ectomycorrhizal fungi and a beneficial Pseudomonas sp. strain GM41 for their effect on plant growth (height, stem girth, leaf, and root growth) and growth rate over time of four poplar genotypes of Populus trichocarpa. We also compare the total organic carbon and plant exometabolites profiles produced by these different poplar genotypes when colonized by the microbial consortium. We determined that when comparing the treatments to the control, plant growth parameters were not significantly different across the poplar genotypes eight weeks post-inoculation. However, total organic carbon and exometabolite profiles were significantly different between the genotypes and due to the treatments. These findings indicate that this microbial consortium can induce early and different signaling responses in poplar.
2022-10-24 | MSV000090574 | MassIVE
Project description:Bacterial cancer therapies face precision and safety challenges, which limit their clinical application. This study presents a triple-engineered Salmonella typhimurium strain (OITE-bacteria), designed for targeted cancer therapy, inspired by octopus biology and leveraging synthetic biology and biomimetic principles. The strain incorporates SpyTag proteins on the outer membrane, allowing covalent attachment of SpyCatcher-fused quadruple RGD peptides to enhance tumor adhesion via integrin αvβ3 interactions. This promotes bacterial enrichment in various solid tumors and lung metastases. Subsequently, Quorum sensing induces expression of strain HtrA protein within tumors, enhancing extracellular polysaccharide-mediated immunogenicity for activating immune cells. Additionally, the bacteria locally release anti-PD1 nanobodies to anti-immunosuppressive. In murine models, OITE-bacteria achieved a ninefold increase in tumor colonization within 12 hours and sustained melanoma growth suppression for over 40 days, with a 100% response rate. This modular approach, integrating safety and efficacy, provides a new strategy in microbial therapeutics for solid tumors.
2026-01-01 | GSE250146 | GEO