Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNAseq Transcriptomic Analyses of European Ancestry samples in MGS Dataset

ABSTRACT: RNAseq Transcriptomic Analyses of European Ancestry samples in MGS Dataset

PROVIDER: PRJNA589916 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNAseq Transcriptomic Analyses of European Ancestry samples in MGS Dataset

Project description:RNAseq Transcriptomic Analyses of European Ancestry samples in MGS Dataset

| PRJNA589915 | ENA

Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry

Project description:Characterization of ancestry-linked peptide variants in disease-relevant patient tissues represents a foundational step to connect patient ancestry with molecular disease pathogenesis. Nonsynonymous single nucleotide polymorphisms (SNPs) encoding missense substitutions within tryptic peptides exhibiting high allele frequencies in European, African, and East Asian populations, termed peptide ancestry informative markers (pAIMs), were prioritized from 1000 genomes. In silico analysis shows that as few as 20 pAIMs can determine ancestry proportions similarly to >260K SNPs (R2=0.9905). Multiplexed proteomic analysis of >100 human endometrial cancer cell lines and uterine leiomyoma (ULM) tissues combined resulted in the quantitation of 62 pAIMs that correlate with self-described race and genotype-confirmed patient ancestry. Candidates include a D451E substitution in GC vitamin D-binding protein previously associated with altered vitamin D levels in African and European populations. These efforts describe a generalized set of markers for proteoancestry assessment that will further support studies investigating the impact of ancestry on the human proteome and how this relates to the pathogenesis of uterine neoplasms.

2022-02-16 | PXD029323 | Pride

Differences in microRNA expression in breast cancer between women of African and European ancestry

Project description:Differences in microRNAs have not been well studied as potential mechanisms underlying the breast cancer disparity. A number of miRNAs were differentially expressed not only by tumor subtype but by ancestry, indicating differences in tumor biology of breast cancer between women of African and European ancestry. Findings may contribute to a better understanding of the biology of breast cancer disparities and help develop more targeted preventative and therapeutic strategies.

2018-12-06 | GSE117452 | GEO

RNA splicing and aggregate gene expression differences between lung squamous cell carcinoma from patients of West African and European ancestry

Project description:Study of genes that are differentially spliced and differentially expressed between African Americans and whites with lung squamous cell cancer. Despite racial disparities in lung cancer, the molecular landscape of lung cancer in patients of African ancestry remains underexplored. Population-related differences in alternative RNA splicing have not been explored. We identified differentially spliced genes and differentially expressed genes between lung squamous cell carcinoma from patients of West African and European ancestry.

2021-01-31 | GSE137291 | GEO

GENEVA GWAS of Prematurity and its Complications - European Ancestry

Project description:GENEVA GWAS of Prematurity and its Complications - European Ancestry

| PRJNA75461 | ENA

Comparative transcriptome of astrocytes in MGS

Project description:Comparative gene expression analysis of astrocytes cultured with conventional method or in MGS.

2024-01-09 | GSE241716 | GEO

CNV analysis of 233 individuals of European ancestry and 6 individuals of non-European ancestry with cleft lip and/or cleft palate

Project description:CNV analysis of 233 individuals of European ancestry and 6 individuals of non-European ancestry with cleft lip and/or cleft palate

| PRJNA874304 | ENA

Precision medicine for dilated cardiomyopathy in European and African ancestry

Project description:Precision medicine for dilated cardiomyopathy in European and African ancestry

| PRJNA771722 | ENA

Precision medicine for dilated cardiomyopathy in European and African ancestry

Project description:Precision medicine for dilated cardiomyopathy in European and African ancestry

| PRJNA771723 | ENA

Comparative transcriptome of cancer cells cultured in MGS

Project description:Comparative gene expression analysis of PC9 versus PC9-BrM4 versus PC9-AMG human lung cancer cells cultured in MGS

2024-01-09 | GSE242020 | GEO