Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

TOR targets a nuclear RNA processing network to support cell proliferation and control developmental gene expression [ChIP-chip]

ABSTRACT: TOR targets a nuclear RNA processing network to support cell proliferation and control developmental gene expression [ChIP-chip]

PROVIDER: PRJNA597152 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

TOR targets a nuclear RNA processing network to support cell proliferation and control developmental gene expression [ChIP-chip]

Project description:Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast. Occupancy profiling of MYC-tagged or GFP-tagged Pir1 protein in fission yeast. Occupancy profiling of FLAG-tagged Rec12-DNA linkages during meiosis of fission yeast.

2020-12-22 | GSE142486 | GEO

TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation

Project description:TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation

| PRJNA597150 | ENA

Tor tor

Project description:Tor tor overview

| PRJNA973154 | ENA

Tor tor

Project description:Tor tor Partial genome sequencing

| PRJNA638510 | ENA

rnai tor time course - The signalization way TOR/PTEN in Arabidopsis

Project description:gnp_blan06_torpten - rnai tor time course - The impact of the TOR pathway on growth and stress responses. Modification of translational and transcriptional profiles in Tor-inducible RNAi mutants and identification of TOR targets.

2011-01-07 | GSE25701 | GEO

tor-Transcriptome analysis of TOR (Target of Rapamycin) mutant.

Project description:ra03-07_tor - tor - Study of 2 TOR mutants (7817 Strong, 7846 weak) - Mutant vs wild type on different nitrogen conditions (10mM=control and 100uM) Keywords: treated vs untreated comparison,wt vs mutant comparison

2007-06-20 | GSE7987 | GEO

rnai tor time course - The signalization way TOR/PTEN in Arabidopsis

2011-01-07 | E-GEOD-25701 | biostudies-arrayexpress

dark hypocotyls tor rnai-Dark hypocotyls TOR RNAi

Project description:fapesp-bra-inra-10-01_bioen_hypocotyl - dark hypocotyls tor rnai - Transcriptional comparison between 2 TOR RNAi mutants versus GUS control. - Sowing after 24h imbibition at 4°C in the dark, on MS1/5, no sucrose, 10 mM ethanol, 8 g/l agar, vertical growth with 3h light, 6 days growth in the dark (20°C), hypocotyls were harvested under green light ; cotyledons and root were removed.

2012-10-10 | GSE41404 | GEO

TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation.

Project description:Cell proliferation and differentiation require signalling pathways that enforce appropriate and timely gene expression. We find that Tor2, the catalytic subunit of the TORC1 complex in fission yeast, targets a conserved nuclear RNA elimination network, particularly the serine and proline-rich protein Pir1, to control gene expression through RNA decay and facultative heterochromatin assembly. Phosphorylation by Tor2 protects Pir1 from degradation by the ubiquitin-proteasome system involving the polyubiquitin Ubi4 stress-response protein and the Cul4-Ddb1 E3 ligase. This pathway suppresses widespread and untimely gene expression and is critical for sustaining cell proliferation. Moreover, we find that the dynamic nature of Tor2-mediated control of RNA elimination machinery defines gene expression patterns that coordinate fundamental chromosomal events during gametogenesis, such as meiotic double-strand-break formation and chromosome segregation. These findings have important implications for understanding how the TOR signalling pathway reprogrammes gene expression patterns and contributes to diseases such as cancer.

| S-EPMC9260697 | biostudies-literature

TOR early response genes in plant shoots

Project description:We identified TOR target genes using three different TOR active site inhbitors AZD8055, TORIN1 and KU63749 in Arabidopsis thaliana shoots

2023-02-01 | GSE197099 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data