Project description:Although vascular dementia (VaD) is the second most prevalent form of dementia, there is currently a lack of effective treatments. Tilianin, isolated from the traditional drug Dracocephalum moldavica L., may protect against ischemic injury by inhibiting oxidative stress and inflammation via the CaMKII-related pathways but with weak affinity with the CaMKII molecule. microRNAs (miRNAs), functioning in post-transcriptional regulation of gene expression, may play a role in the pathological process of VaD via cognitive impairment, neuroinflammatory response, and neuronal dysfunction. This study aimed to investigate the role of tilianin in VaD therapy and the underlying mechanism through which tilianin regulates CaMKII signaling pathways based on miRNA-associated transcriptional action.
2023-04-02 | GSE228494 | GEO
Project description:Chromosome-level genome assembly of Dracocephalum rupestre
| PRJNA1108787 | ENA
Project description:Complete plastid genome sequence of Dracocephalum rupestre (Lamiaceae)
| PRJNA883819 | ENA
Project description:Chloroplast Genome of the Dragonhead Herb, Dracocephalum heterophyllum