Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cell lines including SW480 and SW620

ABSTRACT: Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cell lines including SW480 and SW620

PROVIDER: PRJNA602485 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10919162.fastq.gz	Fastqsanger.gz
	SRR10919163.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cell lines including SW480 and SW620

Project description:Purpose: The goals of this study are to compare the differentially expressed miRNAs between SW480 and SW620. Methods:Total RNA of two samples was used to prepare the miRNA sequencing library.The libraries were denatured as single-stranded DNA molecules, captured on Illumina flow cells, amplified in situ as clusters and finally sequenced for 50 cycles on Illumina NextSeq. Results:We found 72 miRNAs were downregulated on the basis of fold-change less than 0.5. However,total 160 miRNAs were upregulated on the basis of fold-change greater than 2. Conclusions: Our study represents the detailed analysis of SW480 and SW620, generated by RNA-seq technology. Our results show that NGS offers a comprehensive and more accurate quantitative and qualitative evaluation of miRNA content. We conclude that RNA-seq based transcriptome characterization would expedite genetic network analyses and permit the dissection of complex biologic functions.

2020-01-22 | GSE144002 | GEO

MicroRNA expression profile between human colorectal cancer SW480 and SW620 cell line

2016-08-01 | GSE72412 | GEO

MicroRNA expression profile between human colorectal cancer SW480 and SW620 cell line

Project description:Two isogenic human colorectal cancer cell lines (primary SW480 cell line and its lymph node metastatic variant SW620 cell line),as an in vitro metastatic model. We have demonstrated that SW620 cell line possesses high metastasis potential and SW480 cell linepossesses low metastatic potential. We want to compare the whole cell microRNAs profiles of two isogenic colorectal cancer cell lines (SW480 and SW620 cell line), to gain an insight into the molecular events of colon cancer metastasis.

2016-08-01 | E-GEOD-72412 | biostudies-arrayexpress

Ribosome-bound lncRNAs between SW620 and SW480

Project description:The differential ribosome-bound lncRNAs between SW620 and SW480 were investigated by RNA-seq.

2020-05-26 | GSE139407 | GEO

Bulk Transcriptome Profiling of SW480 and SW620 tumors from zebrafish xenografts

Project description:Buk transcriptome profiling of SW480 and SW620 tumors dissected from zebrafish xenografts at 2dpi.

2021-01-14 | GSE163746 | GEO

Ribosome-bound lncRNAs between SW620 and SW480

Project description:Ribosome-bound lncRNAs between SW620 and SW480

| PRJNA579558 | ENA

TET2 binding protein of human colon cancer cell SW480-SW620

Project description:This project was aimed to identify proteins interatcted with TET2 and the differences between SW480 and SW620.

2023-10-24 | PXD020080 | Pride

High-throughput mass spectrometry analysis of N-glycans and protein markers after FUT8 knockdown in the syngeneic SW480/SW620 colorectal cancer cell model

Project description:MS analysis of proteins from FUT8-knockdown SW480 and SW620 colorectal cancer cells

2024-03-21 | PXD050012 | Pride

24h time-course microarray study of SW480 and SW620 cells

Project description:A 24h time-course array study was performed to analyse the different circadian phenotypes of SW480 and SW620 cells, a cell line from a primary tumor and a metastatic cell line from the same patient. Samples were taken every three hours for a period of 24h so that 9 time-points could be analysed for each cell line.

2018-07-23 | E-MTAB-5876 | biostudies-arrayexpress

Identification of differentially expressed miRNAs between SW480 and SW620 spheroid cultures [miRNA]

Project description:The colorectal cancer (CRC) cell line pair SW480/SW620 is an accepted model to study CRC progression and metastasis formation. Studying miRNA expression differences might allow to uncover molecular mechanisms that underlie metastasis initiation Both cell lines are derived from the same patient, but at different stages of the disease. They might show differences in tumor-initiating cell (TIC) potential.

2018-04-12 | GSE89522 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data