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NHLBI TOPMed: Genomic Summary Results for the Trans-Omics for Precision Medicine Program

ABSTRACT: NHLBI TOPMed: Genomic Summary Results for the Trans-Omics for Precision Medicine Program

PROVIDER: PRJNA605040 | ENA |

REPOSITORIES: ENA

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NHLBI TOPMed: Genomic Summary Results for the Trans-Omics for Precision Medicine Program

Project description:NHLBI TOPMed: Genomic Summary Results for the Trans-Omics for Precision Medicine Program

| PRJNA605039 | ENA

NHLBI TOPMed: Trans-Omics for Precision Medicine for Congestive Heart Failure (TOPCHeF)

Project description:NHLBI TOPMed: Trans-Omics for Precision Medicine for Congestive Heart Failure (TOPCHeF)

| PRJNA635178 | ENA

NHLBI TOPMed: Trans-Omics for Precision Medicine for Congestive Heart Failure (TOPCHeF)

Project description:NHLBI TOPMed: Trans-Omics for Precision Medicine for Congestive Heart Failure (TOPCHeF)

| PRJNA635179 | ENA

NHLBI TOPMed: Trans-Omics for Precision Medicine Whole Genome Sequencing Project: ARIC

Project description:<p> Participants from the Atherosclerosis Risk in Communities (ARIC) Study, a large population-based longitudinal cohort study, have been included in this Project and whole genome sequencing will be performed to contribute to analyses of early-onset atrial fibrillation and venous thromboembolism. Additional phenotype and genotype data are available for these individuals on dbGaP and can be accessed through the parent ARIC Cohort accession (phs000280.v3.p1). The National Heart, Lung and Blood Institute (NHLBI) Trans-Omics for Precision Medicine (TOPMed) program is designed to generate scientific resources to enhance understanding of fundamental biological processes that underlie heart, lung, blood and sleep disorders (HLBS). It is part of a broader Precision Medicine Initiative, which aims to provide disease treatments that are tailored to an individual's unique genes and environment. TOPMed will contribute to this initiative through the integration of whole genome sequencing (WGS) and other -omics (e.g., metabolic profiles, protein and RNA expression patterns) data with molecular, behavioral, imaging, environmental, and clinical data. In doing so this program seeks to uncover factors that increase or decrease the risk of disease, identify subtypes of disease, and develop more targeted and personalized treatments. The Whole Genome Sequencing (WGS) Project is part of NHLBI's TOPMed program and serves as an initial step for the larger initiative.</p>

| phs001211 | dbGaP

NHLBI TOPMed: Partners HealthCare Biobank

Project description:NHLBI TOPMed: Partners HealthCare Biobank

| PRJNA300701 | ENA

NHLBI TOPMed: The Women's Health Initiative

Project description:NHLBI TOPMed: The Women's Health Initiative

| PRJNA352302 | ENA

NHLBI TOPMed: Cardiovascular Health Study (CHS)

Project description:NHLBI TOPMed: Cardiovascular Health Study (CHS)

| PRJNA385053 | ENA

NHLBI TOPMed: Barbados Asthma Genetics Study

Project description:NHLBI TOPMed: Barbados Asthma Genetics Study