Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes
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ABSTRACT:
PROVIDER: PRJNA610180 | ENA |
REPOSITORIES: ENA
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Project description:TruCulture human whole blood ex vivo stimulation was performed on 17 healthy individuals and 17 post-onset type 1 diabetics, then gene expression was analyzed using Nanostring to characterize stimulated innate immune responses. Ex vivo whole blood stimulation revealed higher induced IFN-1 responses in type 1 diabetes as compared to healthy controls.
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