Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Intestinal microbiome of pediatric patients with primary sclerosing cholangitis in association with ulcerative colitis

PROVIDER: PRJNA610934 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11277400_1.fastq.gz	Fastqsanger.gz
	SRR11277400_2.fastq.gz	Fastqsanger.gz
	SRR11277401_1.fastq.gz	Fastqsanger.gz
	SRR11277401_2.fastq.gz	Fastqsanger.gz
	SRR11277402_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 102

Similar Datasets

Common functional alterations identified in blood transcriptome of autoimmune cholestatic liver and inflammatory bowel diseases

Project description:Primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and inflammatory bowel diseases (IBDs), including Crohn’s disease (CD) and ulcerative colitis (UC), are heterogeneous chronic autoimmune diseases that may share underlying pathogenic mechanisms. Herein, we compared simultaneously analyzed blood transcriptomes from patients with PBC, PSC, and IBD.

2019-05-01 | GSE119600 | GEO

Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis

Project description:This study is being done to: To attempt to increase the detection of precancerous colon tissue in patients with chronic ulcerative colitis and primary sclerosing cholangitis; To determine if an investigational scope that can look at the lining of the colon in different ways will help the doctor identify abnormal tissue in patients with chronic ulcerative colitis and concurrent primary sclerosing cholangitis; and To determine if this investigational scope can accurately detect precancerous or cancerous tissue in patients with chronic ulcerative colitis that are known to have had cancerous or precancerous tissue in the past.

| 2048547 | ecrin-mdr-crc

Influence of GPR35 deficiency on the ileal and macrophage transcriptome

Project description:Mutations in GPR35 (G protein coupled receptor 35) are linked to ulcerative colitis and primary sclerosing cholangitis. How GPR35, which interacts with the Na/K-ATPase to determine ion transport, influences the transcriptome of macrophages and the ileum is unknown. Here compare transcript expression in bone marrow-derived macrophages and isolated ileum from mice deficient in GPR35 (knockout) with wild type mice by bulk RNA sequencing.

2025-02-07 | GSE252926 | GEO

human gut metagenome

Project description:16S amplicon sequence analysis of stools from patients with pediatric Primary Sclerosing Cholangitis compared with Ulcerative Colitis and healthy controls

| PRJDB4871 | ENA

human saliva metagenome

Project description:16S amplicon sequence analysis of saliva from patients with pediatric Primary Sclerosing Cholangitis compared with Ulcerative Colitis and healthy controls

| PRJDB5650 | ENA

Large-scale whole blood RNA-Seq identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis

Project description:Large-scale whole blood RNA-Seq identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis

| PRJNA736966 | ENA

Project description:Gut microbiota and gut mycobiota of patients affected by ulcerative colitis (UC) and primary sclerosing cholangitis (PSC) Raw sequence reads

| PRJNA935155 | ENA

Klebsiella pneumoniae

Project description:Klebsiella pneumoniae isolated from patients with primary sclerosing cholangitis

| PRJDB7545 | ENA

feces metagenome

Project description:Klebsiella pneumoniae isolated from patients with primary sclerosing cholangitis

| PRJDB7573 | ENA

Microarray analysis from paired biopsies from ileal pouch-anal anastomosis surgery patients with ulcerative colitis and familial adenomatous polyposis

Project description:Pouchitis is a common complication for ulcerative colitis (UC) patients with ileal pouch-anal anastomosis (IPAA) surgery. Similarly to IBD, both innate host factors such as genetics, and environmental stimuli including the tissue-associated microbiome have been implicated in the pathogenesis. In this study, we make use of the IPAA model of inflammatory bowel disease (IBD) to carry out a study associating mucosal host gene expression with the microbiome and corresponding clinical outcomes. In order to determine how host gene expression might influence, or be influenced by the tissue associated microbiome, we analyzed 205 IPAA patients with biopsies collected from the pouch and afferent limb for host transcriptomics and 16S rDNA gene sequencing. Metadata included antibiotic use, inflammation score, and clinical classification. To achieve power for a genome-wide microbiome-transcriptome association study, we used principal component analysis to reduce OTUs and host transcripts to eigengenes and eigenclades explaining 50% of observed variance. These were subsequently tested for significant covariation with one another and/or outcome using multivariate linear modeling.

2015-01-27 | E-GEOD-65270 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data